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An Introduction
to the Takegoshi Lab

Spirit behind the research

The molecule, the ingredient of the real world, is too small to be visible by the naked eye. But its shape, its motion as well as electron distribution around it govern the properties of matter, and thereby the way the real world is. We are trying to step into the realm of molecules through the "window" of Nuclear Magnetic Resonance (NMR) spectroscopy.

Atomic nuclei possess magnetic moment called the spin, whose classical analogue is something like a bar magnet. The NMR spectroscopy enables us to communicate with the nuclear spins by making use of radio waves of a frequency range of about a few to a thousand megaherts. Remarkably, the NMR signal from a nulear spin reflect its environment, including the shape, motion, and electronic strucrue of the molecule to which it belongs. Thus it is possible to extract static and dynamic molecular structure by analysing the NMR signal. Moreover, we can design an NMR experiment so that the nuclear spins in interest send us specific information as to, e.g., interatomic distance, electronic environment, the order of alignment, etc. This is one of what we do in our daily research: methodology of NMR. Sometimes our ideas require us to develop new hardware in order to put it into practice. In this respect, engineering aspects of NMR spectroscopy are also of great interest to us. And most importantly, we believe that the new techniques and new hardwares of NMR spectroscopy that we develop would one day enable us to observe what have been invisible so far. These include Amyloid-beta, the key molecule to fight against the Altzheimer desease, inclusion compounds, polymers, nanoparticles, superconducting materials.

In short, we are trying to create new approaches of NMR in order to see the unseen, and thereby gain new insights into science.

NMR facilities in our laboratory.