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News
[2011.2.15] Global COE Seminar
Click here for the previous news. A seminar presented by Prof. Marek Pruski (Iowa State University, USA) is scheduled on March 11, 2011 at 15pm in Rm 571, Building no 6. Cllick here for details. 。 [2010.7.14] Swollen Kamo river.  [2010.6.23] Global COE Seminar A seminar presented by Dr. Konstantin I. Momot is scheduled on July 13, 2010 at 15pm in Rm 571, Building no 6. Cllick here for details. 。 [2010.5.15] 1st Japan-France solid-state workshop for neophytes has been finished. Photos are uploaded here.  [2010.1.13] Happy birthday, Mizuno!  [2008.11.19] Congratulations on Inukai's young poster presentation reward (solid-state NMR) in 48th annual Japanese NMR Conference! Double-resonance magic-angle coil spinning Munehiro Inukai1 and Kazuyuki Takeda1 (1Kyoto Univ.) |
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New publications
[2012.1.10]
A paper on QUantitative Cross Polarization (QUCP）under a moderate MAS speed of 23 kHz has been published in Journal of Magnetic Resonance.
Kazuyuki Takeda, Yasuto Noda, K. Takegoshi, Olivier Lafon, Julien Trébosc, Jean-Paul Amoureux
Quantitative cross-polarization at magic-angle spinning frequency of about 20 kHz
Journal of Magnetic Resonance 214 (2012) 340-345; doi:10.1016/j.jmr.2011.11.014
[2012.1.10]
A paper on "DISK-MAS", which has realized nondestructive MAS of thin films for the first time, has been published inJournal of Magnetic Resonance.
Munehiro Inukai, Yasuto Noda, Kazuyuki Takeda
Nondestructive high-resolution solid-state NMR of rotating thin films at the magic-angle
Journal of Magnetic Resonance 213 (2011) 192-195; doi:10.1016/j.jmr.2011.09.013
[2011.10.31]
A monograph on NMR spectroscopy has been published (Language: Japanese).
K. Takegoshi
磁気共鳴－ＮＭＲ －核スピンの分光学－
ISBN978-4-7819-1295-0
[2011.10.31]
A paper on binding of mannose on pradimicin has been published in J. Am. Chem. Soc.. This work has been done in collaboration with Dr. Nakagawa at RIKEN.
Y. Nakagawa, T. Doi, Y. Masuda, K. Takegoshi, Y. Igarashi, and Y. Ito
Mapping of the Primary Mannose-Binding Site of Pradimicin A
J. Am. Chem. Soc. 133, 17485-17493 (2011); doi: 10.1021/ja207816h
[2011.10.5]
A review article on application of the OPENCORE NMR spectrometer has been published in Annual Reports on NMR Spectroscopy.
Kazuyuki Takeda
Chapter 7 - Highly Customized NMR Systems Using an Open-Resource, Home-Built Spectrometer
Annual Reports on NMR Spectroscopy 74 (2011) 355-393; doi:10.1016/B978-0-08-097072-1.00007-8
[2011.9.26]
A paper studying interactions between curcumin molecules and Aβ42 fibrils has been published in Bioorg. Med. Chem.. This work has been done by Yuichi Masuda, a former posdoc in our lab and presently an assistant professor in Tohoku University, in collaboration with a group headed by Prof. Irie in Graduate School of Agriculture, Kyoto Univ.
Y. Masuda, M. Fukuchi, T. Yatagawa, M. Tada, K. Takeda, K. Irie, Y. Monobe, T. Imazawa, and K. Takegoshi
Solid-state NMR analysis of interaction sites of curcumin and 42-residue amyloid β-protein fibrils
Bioorg. Med. Chem., 19 (2011) 5967-5974; doi:10.1016/j.bmc.2011.08.052
[2011.7.20]
Solid-state NMR studies on binding of Pradimicin A to Mannose has been published in Angew. Chem. This work has been done in collabolation with Dr. Nakagawa in RIKEN.
Y. Nakagawa, Y. Masuda, K. Yamada, T. Doi, K. Takegoshi, Y. Igarashi, and Y. Ito
Solid-State NMR Analysis of Ca2+-Dependent Mannose Binding of Pradimicin A
Angew. Chem. Int. Ed., 50 (2011) 6084-6088; doi: 10.1002/anie.201007775
[2011.7.8]
A paper on 19F MAS NMR of paramagnetic graphite intercalation compounds has been published inCarbon.
Kazuma Gotoh, Kazuyuki Takeda, Michael M. Lerner, Yoshimi Sueishi, Shinpei Maruyama, Atsushi Goto, Masataka Tansho, Shinobu Ohki, Kenjiro Hashi, Tadashi Shimizu, Hiroyuki Ishida
Analysis of bis(trifluoromethylsulfonyl)imide-doped paramagnetic graphite intercalation compound using 19F very fast magic angle spinning nuclear magnetic resonance
CARBON 49 (2011) 4059–4073; doi:10.1016/j.carbon.2011.05.009
[2011.6.22]
A paper on signal post-processing has been published in Journal of magnetic resonance. In this work we discuss statistical data processing, namely, Phase Standard Deviation and Phase Covariance, which can complement the conventional approach of signal averaging.
J. Fukazawa, K. Takeda, and K. Takegoshi
Post-processing of individual signals for de-noising
J. Magn. Reson. 211 (2011) 52-59; doi:10.1016/j.jmr.2011.04.003
[2011.6.16]
A paper on high-field and fast-MAS NMR studies of amyloid peptides has been published in Journal of Biomolecular NMR.
M. Weingarth, Y. Masuda, K. Takegoshi, G. Bodenhausen, and P. Tekely
Sensitive 13C-13C Correlation Spectra of Amyloid Fibrils at very High Spinning Frequencies and Magnetic Fields
J. Biomol. NMR. 50 (2011) 129-136; doi:10.1007/s10858-011-9501-9
[2011.3.2]
A paper describing our recent development of dynamic receiver gain increment during signal acquisition (the APRICOT method) has been published in Journal of magnetic resonance.
K. Takeda and K. Takegoshi
Noise reduction by dynamic signal preemphasis
J. Magn. Reson. 208 (2011) 305-308; doi:10.1016/j.jmr.2010.11.017
[2010.10.20]
A paper describing acceleration of 1H spin diffusion by 2H double-quantum decoupling in dynamic nuclear polarization using photo-excited triplet electrons has been published in Journal of Chemical Physics.
M. Negoro, K. Nakayama, K. Tateishi, A. Kagawa, K. Takeda, and M. Kitagawa
2H-decoupling-accelerated 1H spin diffusion in dynamic nuclear polarization with photoexcited triplet electrons
J. Chem. Phys. 133, 154504 (2010); doi:10.1063/1.3493453
[2010.9.10]
A paper on a new method of signal processing using covariance of the phases of the excitation pulse and the NMR signal has been pulished in Phys. Chem. Chem. Phys..
J. Fukazawa and K. Takegoshi
Phase Covariance in NMR Signal
Phys. Chem. Chem. Phys. 12, 11225-11227 (2010).
[2010.5.21]
The work on total compensation of rf-pulse transients, an extention of our previous study on active compensation of the amplitude transients of rf pulses, has been published in Journal of Magnetic Resonance. In this work we propose how to actively compensate amplitude and phase transients simultaneously.
Y. Tabuchi, M. Negoro, K. Takeda, M. Kitagawa
Total compensation of pulse transients inside a resonator
J. Magn. Reson. 204 (2010) 327-332.
[2010.3.25]
A paper on overtone NMR, a work done by Fukazawa in collaboration with Prof. Shoji group (Gumma Univ.), has finally been published in Journal of American Chemical Society!
J. Fukazawa, S. Kato, T. Ozaki, A. Shoji and K. Takegoshi
14N Quadrupolar Coupling of Amide Nitrogen and Peptide Secondary Structure As Studied by Solid-State NMR Spectroscopy
J. Am. Chem. Soc. 132, 4290-4294 (2010).
[2010.1.3]
A paper on an extension of magic angle coil spinning (MACS) to double-resonance experiments has been published in Journal of Magnetic Resonance. Contributed by Inukai.
M. Inukai and K. Takeda
Double-resonance magic angle coil spinning
J. Magn. Reson. 202, 274-278 (2010).
[2009.12.1]
A study on determination of themodynamic parameters (ΔS, ΔH) associated with αcoil-βsheet secondary structure transition in poly(β-benzyl L-aspartate) in the solid-state has been published in Macromolecules. This work has been contributed by Nakanishi during her master course.
A. Nakanishi, A. Shoji, K. Takegoshi
Thermodynamics in Conformational Transition of Poly(β-benzyl L-aspartate) As Studied by High-Resolution Solid-State 13C NMR Spectroscopy
Macromolecules, 42, 9307-9311 (2009).
[2009.7.14]
A monograph on dynamic nuclear polarization using photo-excited triplet electron spins has been published from VDM Verlag.
Kazuyuki Takeda
Triplet State Dynamic Nuclear Polarization
ISBN: 978-3639170986
Click here for editorial review.
[2009.4.30]
A paper on a field-cycling system developed for studies on dynamic nuclear polarization (DNP) using photo-excited triplet electron spins has been published in Review of Scientific Instruments.
Akinori Kagawa, Makoto Negoro, Kazuyuki Takeda, Masahiro Kitagawa
Magnetic-field cycling instrumentation for dynamic nuclear polarization-nuclear magnetic resonance using photoexited triplets
Rev. Sci. Instrum., 80 (2009) 044705.
[2009.3.23]
A paper on active compensation of rf-pulse transients has been published in Journal of Magnetic Resonance. This paper is hilighted in the cover sheet of Journal of Magnetic Resonance, Volume 197, Issue 2!
Kazuyuki Takeda, Yutaka Tabuchi, Makoto Negoro, Masahiro Kitagawa
Active compensation of rf-pulse transients
J. Magn. Reson., 197 (2009) 242-244.
[2008.3.6]
A paper on the optimization of dynamic nuclear polarization (DNP) using electron spins in the photo-excited triplet state by means of partial deuteration of the sample material has been published in Journal of Magnetic Resonance.
Akinori Kagawa, Yu Murokawa, Kazuyuki Takeda, and Masahiro Kitagawa
Optimization of 1H spin density for dynamic nuclear polarization using photo-excited triplet electron spins
J. Magn. Reson., 197 (2009) 9-13.
[2009.1.26]
A paper on cross polarization using composite zero-degree pulses (COMPOZER) has been published in Journal of Magnetic Resonance.
M. Fukuchi, A. Ramamoorthy, and K. Takegoshi
Efficient Cross-Polarization Using a Composite 0o Pulse for NMR Studies on Static Solids
J. Magn. Reson., 196, 105-109 (2009).
[2009.1.19]
A paper on Aβ42, the causative agent for the Alzheimer's desease, has been published in ChemBioChem. This work has been done in collaboration with the Irie group at Graduate School of Agriculture, Kyoto Univ.
Y. Masuda, S. Uemura, R. Ohashi, A. Nakanishi, K. Takegoshi, T. Shimizu, T. Shirasawa, and K. Irie
Identification of Physiological and Toxic Conformations in Aβ42
ChemBioChem, 10, 287-296 (2009).
[2008.12.12]
An article on the COCODARR technique has been published in Solid State Nuclear magnetic Resonance!
Masashi Fukuchi, K. Takegoshi
Combination of 13C-13C COSY and DARR (COCODARR) in solid-state NMR
Solid State Nucl. Magn. Reson., 34, 151-153 (2008).
[2008.10.20]
A paper on 11B NMR studies of boron-doped diamonds has been published in Diamond Relat. Mater. This work has been done in collaboration with Shimizu group in NIMS.
M. Murakami, T. Shimizu, M. Tansho, Y. Takano, S. Ishii, E.A. Ekimov, V.A. Sidorov, H. Sumiya, H. Kawarada, K. Takegoshi
Characterization of Boron-doped Diamonds Using 11B High-resolution NMR at High Magnetic Fields
Diamond Relat. Mater., 17 1835-1839 (2008).
[2008.10.20]
A paper on Aβ42, known to cause the Altzheimer desease, has been published in Biosci. Biotechnol. Biochem.This work has been done in collaboration with the Irie group in Graduate School of Agriculture, Kyoto Univ.
Y. Masuda, A. Nakanishi, R. Ohashi, K. Takegoshi, T. Shimizu, T. Shirasawa, and K. Irie
Verification of the Intermolecular Parallelβ-Sheet in E22K-Aβ42 Aggregates by Solid-state NMR Using Rotational Resonance: Implications for the Supramolecular Arrangement of the Toxic Conformer of Aβ42
Biosci. Biotechnol. Biochem., 72, 2170-2175 (2008).
[2008.10.7]
A paper on Double-Acquisition has been published in Journal of Magnetic Resonance!
Masashi Fukuchi, Munehiro Inukai, Kazuyuki Takeda, K. Takegoshi
Double-acquisition: Utilization of discarded coherences in a 2D separation experiment using the States method
J. Magn. Reson., 194, 300-302 (2008).
[2008.5.28]
A paper on biscontinuous cubic phases, studied in collaboration with Dr. Momot (Australia), has been publised in J. Phys. Chem. B !
K.I. Momot, K. Takegoshi, P.W. Kuchel, and T.J. Larkin
Inhomogeneous NMR Line Shape as a Probe of Microscopic Organization of Biscontinuous Cubic Phases
J. Phys. Chem., B112, 6636-6645 (2008).
[2008.5.28]
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A paper on Aβ42, the material responsible for Alzheimer desease, has been published in Bioorg. Med. Chem. Lett. ! This is a result of collaboration with the Irie Group (Graduate School of Agriculture, Kyoto Univ.). |
Verification of the C-terminal Intramolecular β-sheet in Aβ42 Aggregates using Solid-state NMR: Implications for Potent Neurotoxicity through the Formation of Radicals
Bioorg. Med. Chem. Lett., 18, 3206-3210 (2008).
Click here for a brief introduction to the study on Aβ42.
[2008.5.26]
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A paper on the OPENCORE NMR spectrometer has been published in Journal of Magnetic Resonance! |
OPENCORE NMR: Open-source core modules for implementing an integrated FPGA-based NMR spectrometer
J. Magn. Reson. 192, 218-229 (2008).
Click here for a brief introduction to the OPENCORE NMR spectrometer.
Click here for the main site of the OPENCORE NMR project.
[2008.5.13]
A paper on lineshape analysis of 11B NMR of MgB2 in the normal conductive phase has been published in Journal of the Physical Society of Japan!
T. Yamaji, M. Murakami, J. Fukazawa, T. Shimizu, and K. Takegoshi
Analysis of 11B NMR Powder Lineshape of MgB2 in the Normal Conductive Phase
J. Phys. Soc. Jpn., 77, 044711 (2008).
[2008.4.30]
A paper on development of a cryocoil MAS probe has been published in Review of Scientific Instruments!
Takashi Mizuno, Katsuya Hioka, Koji Fujioka, and K. Takegoshi
Development of a magic-angle spinning nuclear magnetic resonance probe with a cryogenic detection system for sensitivity enhancement
Rev. Sci. Instrum. 79, 044706 (2008).
[2008.4.9]
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A paper on microcoil MQMAS has been published in Concepts in Magnetic Resonance B! |
Studies on multiple-quantum magic-angle-spinning NMR of half-integer quadrupolar nuclei under strong rf pulses with a microcoil
Concepts in Magnetic Resonance 33B, 115-123 (2008).
Click here for a brief introduction to this topic.