Grant-in-Aid for Specially Promoted Research: Design of High-Performance Organocatalysts for the Application to Fine Organic Synthesis SitemapJapanese
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  • Maruoka Group, Department of Chemistry, Graduate School of Science, Kyoto University
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Overview

Research Methods

Based on the information on the design of fine Lewis acids and organometallic catalysts, the rational design of next-generation organocatalyst will be performed in the research project, which is divided into four main research items consisting of "base organocatalyst", "acid organocatalyst", "polyfunctional organocatalyst" and " radical organocatalyst".
Throughout both the basic and applied researches in this project, the applicant would like to aim at the design and synthesis of a series of truly next-generation organocatalysts for practical organic transformations.

Figure 1. Next-Generation Organocatalyst Project
High-Performance Organocatalyst Project



Expected Research Achievements and Scientific Significance

Currently, "organocatalyst" has attracted considerable attention as the third catalyst in organic synthesis in addition to the conventional "biocatalyst" and "metal catalyst". In such an organocatalytic field, the synthesis of “next-generation organocatalyst”, if possible, enables the achievement of new reactivity and selectivity, hitherto not obtainable in the conventional “biocatalyst” and “metal catalyst”. In addition, such next-generation organocatalysts are expected to create the paradigm of the new research and the development of new science and technology.

Figure 2. Research Achievement and Future Effect
Research Achievement and Future Effect