Grant-in-Aid for Scientific Research on Priority Areas Japanese
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Scientific Research on Priority Areas
Advanced Molecular Transformations of Carbon Resources
(Advanced Organic Synthesis Directed toward Process Chemistry)

Abbreviation Name of the Priority Area: Advanced Molecular Transformations
Number of the Priority Area: 444
Term of the Project: October, 2005 ~ March, 2009
Head Investigator: Professor Keiji Maruoka (Graduate School of Science, Kyoto University)


<Research Outline>

The development of excellent synthetic organic reactions to prepare important materials is urgent to Japan, where natural resources are scarce, as a scientific and technological country in order to keep the international superiority in the field of pharmaceutical and chemical industries. In this priority area, we utilize the readily accessible carbon resources efficiently, and pursuit "preparation of important materials for the safety and security of the mankind" by developing (i) new synthetic reactions based on the truly efficient molecular transformations and (ii) the design of high-performance catalysts in consideration of the following keywords, "synthetic power", "environmental harmony", "atom economy", and "sequential transformations". It is to urgently establish the scientific support system which supplies the results of our basic research to "process synthetic organic chemistry" in our industrial world.
 
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<Evaluation Committee>

Shun-ichi Murahashi Okayama University of Science. Professor (Chairman)
Takayuki Shioiri Graduate School of Environmental and Human Sciences, Meijo University. Professor
Masakatsu Shibasaki Graduate School of Pharmaceutical Sciences, The University of Tokyo. Professor
Kohei Tamao Wako Institute, RIKEN. Leader of Frontier Research System
Koichi Narasaka Graduate School of Science, The University of Tokyo. Professor
Ryoji Noyori RIKEN. President
Tetsuo Hiraoka Sankyo Organic Chemicals Co., Ltd. President
Shinji Murai Center for Research and Development Strategy, Japan Science and Technology Agency. Senior Fellow
Hisashi Yamamoto Department of Chemistry, University of Chicago. Professor
Yoshinori Yamamoto Graduate School of Science, Tohoku University. Professor
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<Exective Committee>

Keiji Maruoka Graduate School of Science, Kyoto University. Professor (Chairman)
Kyoko Nozaki Graduate School of Engineering, The University of Tokyo. Professor
Yasutaka Ishii School of Engineering, Kansai University. Professor
Junzo Otera Okayama University of Science. Professor
Tomohiko Ohwada Graduate School of Pharmaceutical Sciences, The University of Tokyo. Professor
Kiyoshi Tomioka Graduate School of Pharmaceutical Sciences, Kyoto University. Professor
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<Group of the Research>

The aim of the scientific research on the priority area is to promote strongly the basic research on organic synthesis directed toward process chemistry, where the following four research groups are set up depending on the kind of carbon resources: "functionallized carbon molecules", "small carbon molecules", "unreactive carbon molecules", and "carbon molecules with π-electron systems" as starting materials of carbon resources.

Group A01: Advanced Molecular Transformations of Functionallized Carbon Molecules
Group Leader: Professor Keiji Maruoka (Kyoto University)
Group A02: Advanced Molecular Transformations of Small Carbon Molecules
Group Leader: Professor Kyoko Nozaki (The University of Tokyo)
Group A03: Advanced Molecular Transformations of Unreactive Carbon Molecules
Group Leader: Professor Yasutaka Ishii (Kansai University)
Group A04: Advanced Molecular Transformations of Carbon Molecules with π-Electron Systems
Group Leader: Professor Junzo Otera (Okayama University of Science)

Each research group is closely related to synthetic organic reactions consisting of "carbon-carbon bond forming reactions", "carbon-hetero atom bond forming reactions", "oxidation-reductions", "functional group transformations", and "sequential transformations".

Each research group has five core researchers, and the present scientific research on the priority area is executed with twenty core research members in total. In addition, during the period of 2006 ~ 2008, many active and progressive researches consisting one person or a small group of researchers are selected and supported for one year with three million yen or less per fiscal year. In particular, challenging research projects with novel ideas by relatively young generations are most welcome. The number of the whole selected research projects is scheduled to be about 130. Such public offering one-year research projects will be raised in the 2006 fiscal year. The partial exchange of project researchers by renewable selections is carried out in the 2007 fiscal year, and is made to continue by the 2008 fiscal year.
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