ミトコンドリアの遺伝子の発現の制御法をつくりました。
http://www.kyoto-u.ac.jp/ja/research/research_results/2017/170616_1.html
植物学の西村先生とDNAで額縁をつくり葉緑体の分裂で重要な酵素の働きを見ました。
http://www.kyoto-u.ac.jp/ja/research/research_results/2017/170512_2.html
ケント大学のMAO先生とナノケージというDNAのいれものをつくりその中でDNAの四重鎖構造を安定化しました。
http://www.kyoto-u.ac.jp/ja/research/research_results/2016/170328_1.html
Thiophene-extended Fluorescent Nucleosides as Molecular Rotor-Type Fluorogenic Sensors for Biomolecular Interactions
Kumagai, T.; Kinoshita, B.; Hirashima, S.; Sugiyama, H.; Park, S.
ACS Sensors 2023, 8, 923-932.
Artificial Intelligence in Microbial Natural Product Drug Discovery: Current and Emerging Role
Sahayasheela, V. J.; Lankadasari, M. B.; Dan, V. M.; Dastager, S. G.; Pandian, G. N.; Sugiyama, H.
Natural Product Reports 2022, 39, 2215-2230.
New Size‐Expanded Fluorescent Thymine Analogue: Synthesis, Characterization, and Application
Hirashima, S.; Han, J.; Tsuno, H.; Tanigaki, Y.; Park, S.; Sugiyama, H.
Chem. Eur. J. 2019, 25, 1-8.
Biomimetic Artificial Epigenetic Code for Targeted Acetylation of Histones
Taniguchi, J.; Feng, Y.; Pandian, G.; Hashiya, F.; Hidaka, T.; Hashiya, K.; Park, S.; Bando, T.; Ito, S.; Sugiyama, H.
J. Am. Chem. Soc., 2018, 140, 7108-7115.
Creation of a Synthetic Ligand for Mitochondrial DNA sequence Recognition and Promoter-Specific Transcription Suppression
Hidaka, T.; Pandian, G.; Taniguchi, J.; Nobeyama, T.; Hashiya, K.; Bando, T.; Sugiyama, H.
J. Am. Chem. Soc., 2017, 139, 8444-8447.
Single-Molecule Mechanochemical Sensing Using DNA Origami Nanostructures
Koirala, D.; Shrestha, P.; Emura, T.; Hidaka, K.; Mandal, S.; Endo, M.; Sugiyama, H.; Mao, H.
Angewanted Chemie International Edition, 2014, 126, 8275-8279.
Alteration of Epigenetic Program to Recover
Memory and Alleviate Neurodegeneration: Prospects of Multi-target Molecules
Pandian, G, N.; Taylor, R, D.; Junetha, S.; Saha, A.; Anandhakumar, A.; Vaijayanthi, T.; Sugiyama, H.
Biomaterials Science, 2014, 2, 1043-1056.
Construction and Characterization of Cy3 or Cy5 Conjugated Hairpin PyrroleImidazole Polyamides Binding to DNA in the Nucleosome
Han, Y, W.; Tusnaka, Y.; Yokota, H.; Matsumoto, T.; Kashiwazaki, G.; Morinaga, H.; Hashiya, K.; Bando, T.; Sugiyama, H.; Harada, Y.
Biomaterials Science, 2014, 2, 297-307.
STRUCTURAL AND FUNCTIONAL ANALYSIS OF PROTEINS
BY HIGH-SPEED ATOMIC FORCE MICROSCOPY
Rajendran, A.; Endo, M.; Sugiyama, H.
Advances in Protein Chemistry and Structural Biology, 2012, 87, 7-48.
Single-Molecule Analysis Using DNA Origami
Rajendran, A.; Endo, M.; Sugiyama, H.
Angewanted Chemie International Edition, 2012, 51, 874-890.
Programmed Two-Dimensional Self-Assembly of Multiple DNA Origami Jigsaw Pieces
Rajendran, A.; Endo, M.; Katsuda, Y.; Hidaka, K.; Sugiyama, H.
ACS Nano, 2011, 5, 665-671.
Programmed-Assembly System Using DNA Jigsaw Pieces.
Endo, M.; Sugita, T.; Katsuda, Y.; Hidaka, K.; Sugiyama, H.
Chemistry A European Journal, 2010, 16, 5326-5368.
Chemical Approaches to DNA Nanotechnology.
Endo, M.; Sugiyama, H.
ChemBioChem, 2009, 10, 2420-2443.
