Welcome to Sugiyama Lab

Welcome to Sugiyama Lab

news

more

publications

more

  • 395. Orthogonal γPNA Dimerization Domains Empower DNA Binders with Cooperativity and Versatility Mimicking that of Transcription Factor Pairs
    Yu, Z.; Hsieh, W-C.; Asamitsu, S.; Hashiya, K.; Bando, T.; Ly, H. D.; Sugiyama, H.
    Chem. Eur. J. in press
  • 394. Construction of Integrated Gene Logic-chip
    Masubuchi, T.; Endo, M.; Iizuka, R.; Iguchi, A.; Yoron, D. H.; Sekiguchi, T.; Qi, H.; Iinuma, R.; Miyazono, Y.; Shoji, S.; Funatsu, T.; Sugiyama, H.; Harada, Y.; Ueda, T.; Tadakuma, H.
    Nature Nanotechnology in press
  • 393. TAMRA-Polypyrrole for A/T Sequence Visualization on DNA Molecules
    Lee, S.; Kawamoto, Y.; Thangavel, V.; Park, J.; Bae, J.; Kim-Ha, J.; Sugiyama, H.; Jo, K.
    Nucleic Acids Research in press
  • 392. Biomimetic Artificial Epigenetic Code for Targeted Acetylation of Histones
    Taniguchi, J.; Feng, Y.; Pandian, G.; Hashiya, F.; Hidaka, T.; Hashiya, K.; Park, S.; Bando, T.; Ito, S.; Sugiyama, H.
    J. Am. Chem. Soc., 2018, 140, 7108-7115.
  • 391. Environment-dependent Self-assembly of DNA Origami Lattices on Phase-separated Lipid Membranes
    Sato, Y.; Endo, M.; Morita, M.; Takinoue, M.; Sugiyama, H.; Murata, S.; Nomura, S.; Suzuki, Y.
    Adv. Mater. Interfaces 2018, 1800437.
  • 390. RUNX1 Positively Regulates the ErbB2/HER2 Signaling Pathway through Modulating SOS1 Expression in Gastric Cancer Cells
    Mitsuda, Y.; Morita, K.; Kashiwazaki, G.; Taniguchi, J.; Bando, T.; Obara, M.; Hirata, M.; Kataoka, R. T.; Muto, M.; Kaneda, Y.; Nakahata, T.; Liu, P. P.; Adachi, S.; Sugiyama, H.; Kamikubo, Y.
    Scientific Reports 2018, 8, 6423.
  • 389. Complexing DNA Origami Frameworks through Sequential Self-assembly Based on Directed Docking
    Suzuki, Y.; Sugiyama, H.; Endo, M.
    Angew.Chem. 2018, 130, 7179-7183.
  • 388. A Synthetic DNA-binding Inhibitor of HES1 Alters the Notch Signaling Pathway and Induces Neuronal Differentiation
    Wei, Y.; Pandian, G.; Yu, Z.; Zou, T.; Li, Y.; Darokar, J.; Hashiya, K.; Bando, T.; Sugiyama, H.
    ACS Omega 2018, 3, 3608-3616.
  • 387. Pip-HoGu: an Artificial Assembly with Cooperative DNA Recognition Capable of Mimicking Transcription Factor Pairs
    Yu, Z.; Guo, C.; Wei, Y.; Hashiya, K.; Bando, T.; Sugiyama, H.
    J. Am. Chem. Soc. 2018, 140, 2426-2429.
  • 386. Triggering Nucleic Acid Nanostructure Assembly by Conditional Kissing Interactions
    Azema, L.; Bonnet-Salomon, S.; Endo, M.; Takeuchi, Y.; Durand, G.; Emura, T.; Hidaka, K.; Dausse, E.; Sugiyama, H.; Toulme, JJ.
    Nucleic Acids Res. 2018, 46, 1052-1058.
  • 385. Simultaneous Binding of Hybrid Molecules Constructed with Dual DNA-binding Components to a G-quadruplex and its Proximal Duplex
    Asamitsu, S.; Obata, S.; Phan, A. T.; Hashiya, K.; Bando, T.; Sugiyama, H.
    Chem. Eur. J. 2018, 24, 4428-4435.
  • 384. Sequence-specific DNA Binding Pyrrole-Imidazole Polyamides and Their Applications
    Kawamoto, Y.; Bando, T.; Sugiyama, H.
    Bioorg. Med. Chem. 2018, 26, 1393-1411.
  • 383. RUNX Transcription Factors Potentially Control E-Selectin Expressions in the Bone Marrow Vascular Niche of Mice
    Morita, K.; Tokushige, C.; Maeda, S.; Kiyose, H.; Noura, M.; Iwai, A.; Yamada, M.; Kashiwazaki, G.; Taniguchi, J.; Bando, T.; Hirata, M.; Kataoka, T. R.; Nakahata, T.; Adachi, S.; Sugiyama, H.; Kamikubo, Y.
    Blood Advances 2018, 5, 509-515.
  • 382. Targeting G-quadruplex DNA as Cognitive Function Therapy for ATR-X Syndrome
    Shioda, N.; Yabuki, Y.; Yamaguchi, K.; Onozato, M.; Li, Y.; Kurosawa, K.; Tanabe, H.; Okamoto, N.; Era, T.; Sugiyama, H.; Wada, T.; Fukunaga, K.
    Nature Medicine 2018, 24, 802-813.
  • 381. DNA Origami Scaffolds as Templates for Functional Tetrameric Kir3 K+ Channels
    Kurokawa, T.; Kiyonaka, S.; Nakata, E.; Endo, M.; Koyama, S.; Mori, E.; Tran, N. H.; Dinh, H.; Suzuki, Y.; Hidaka, K.; Kawata, M.; Sato, C.; Sugiyama, H.; Morii, T.; Mori, Y.
    Angew. Chem. 2018, 57, 2586-2591.
  • 380. Investigating Nucleosome Accessibility for MNase, FeII Peplomycin, and Duocarmycin B2 by Using Capillary Electrophoresis
    Zou, T.; Kizaki, S.; Sugiyama, H.
    ChemBioChem. 2018, 19, 664-668.
  • 379. G-Quadruplex Induction by the Hairpin Pyrrole-Imidazole Polyamide Dimer
    Obata, S.; Asamitsu, S.; Hashiya, K.; Bando, T.; Sugiyama, H.
    Biochem 2018, 57, 498-502.

  • 378. UVA Irradiation of BrU-Substituted DNA in The Presence of Hoechst 33258
    Saha, A.; Kizaki, S.; Han, J. H.; Yu, Z.; Sugiyama, H.
    Bioorg. Med. Chem. 2018, 26, 37-40.
  • 377. Evaluation of Alkylating Pyrrole-Imidazole Polyamide Conjugates by a Novel Method for High-Throughput Sequencer
    Kashiwaszaki, G.; Maeda, R.; Kawase, T.; Hashiya, K.; Bando, T.; Sugiyama, H.
    Bioorg. Med. Chem. 2018, 26, 1-7.
  • 376. Autonomous Feedback Loop of RUNX1-p53-CBFB in Acute Myeloid Leukemia Cells
    Morita, K.; Noura, M.; Tokushige, C.; Maeda, S.; Kiyose, H.; Kashiwazaki, G.; Taniguchi, J.; Bando, T.; Yoshida, K.; Ozaki, T.; Matsuo, H.; Ogawa, S.; Liu, P. P.; Nakahata, T.; Sugiyama, H.; Adachi, S.; Kamikubo, Y.
    Sci. Reports 2017, 7, 16604.
  • 375. Single-Molecule Observation of The Photo Regulated Conformational Dynamics of DNA Origami Nanoscissors
    Willner, E.; Kamada, Y.; Suzuki, Y.; Emura, T.; Hidaka, K.; Dietz, H.; Sugiyama, H.; Endo, M.
    Angew. Chem. Int. Ed. 2017, 56, 15324-15328.
  • 374. A Combination of Visible-Light Photoredox and Metal Catalysis for the Mannich-Type Reaction of N-Aryl Glycine Esters
    Okamura, I.; Park, S.;Han, J.;Notsu, S.;Sugiyama, H.
    Chem. Lett. 2017, 46, 1597-1600.
  • 373. Effective Anti-mRNA Oligonucleotides Show High Releasing Rate of MicroRNA from RNA-Inducing Silencing Complex (RISC)
    Ariyoshi, J.; Matsuyama, Y.; Kobori, A.; Murakami, A; Sugiyama, H.; Yamayoshi, A.
    Nucleic Acid Ther. 2017, 27, 303-308.
  • 372. A Synthetic DNA-binding Inhibitor of SOX2 Guides Human Induced Pluripotent Stem Cells to Differentiate into Cardiac Mesoderm
    Taniguchi, J.; Pandian, G.; Hidaka, T.; Hashiya, K.; Bando, T.; Kim, K. K.; Sugiyama, H.
    Nucleic Acids Res. 2017, 45, 9219-9228.
  • 371. Paradoxical enhancement of leukemogenesis in acute myeloid leukemia with moderately-attenuated RUNX1 expressions
    Morita, K.; Maeda, S.; Suzuki, K.; Kiyose, H.; Taniguchi, J.; Liu, P.P.; Sugiyama, H.; Adachi, S.; Kamikubo, Y. , Blood Adv. 2017, 1, 1440-1451.
  • 370. Protein-driven RNA nanostructured devices that function in vitro and control mammalian cell fate
    Shibata, T.; Fujita, Y.; Ohno, H.; Suzuki, Y.; Hayashi, K.; Komatsu, K.; Kawasaki, S.; Hidaka, K.; Yonehara, S.; Sugiyama, H.; Endo, M.; Saito, H., Nature Comm. 2017, 8, 540.
  • 369. Antiproliferative and Apoptotic Activities of Sequence-Specific Histone Acetyltransferase Inhibitors
    Yu, Z.; Taniguchi, J.; Wei, Y.; Pandian, G.N.; Hashiya, K.; Bando, T.; Sugiyama, H. , Eur. J. Med. Chem. 2017, 138, 320-327
  • 368. Creation of a Synthetic Ligand for Mitochondrial DNA Sequence Recognition and Promoter-Specific Transcription Suppression
    Hidaka, T.; Pandian, G.; Taniguchi, J.; Nobeyama, T.; Hashiya, K.; Bando, T.; Sugiyama, H. , J. Am. Chem. Soc. 2017, 139, 8444-8447.
  • 367. Copper-containing DNA-Silica Mineral Complexes for the Asymmetric Diels-Alder Reaction
    Sakashita, S.; Park, S.; Sugiyama, H. Chemistry Letters. 2017, doi:10.1246/cl.170411.
  • 366. Holliday junction resolvases mediate chloroplast nucleoid segregation
    Kobayashi, Y.; Misumi, O.; Odahara, M.; Ishibashi, K.; Hirono, M.; Hidaka, K.; Endo, M.; Sugiyama, H.; Iwasaki, H.; Kuroiwa, T.; Shikanai, T.; Nishimura, Y. Science. 2017, 356, 631-634.
  • 365. Development of a Vivid FRET System Based on a Highly Emissive dG-dC Analogue Pair
    Han, J.; Yamamoto, S.; Park, S.; Sugiyama, H. Chem. Eur. J. 2017, 23, 7607-7613.