京都大学 物質－細胞統合システム拠点

Sugiyama Laboratory, Kyoto University

Publications :2020

2020 (Highlighted Articles Representing International Collaboration Project)

452. A Near-Infrared Fluorogenic Pyrrole-Imidazole Polyamide Probe for Live-Cell Imaging of Telomeres
Tsubono, Y.; Kawamoto, Y.; Hidaka, T.; Pandian, G.; Hashiya, K.; Bando, T.; Sugiyama, H.
J. Am. Chem. Soc. 2020, 142, 17356-17363.

451. Differentially Expressed Goes on the Growth of Mouse Leydig Cells Treated with Standardized Eurycoma Longifolia Extract
Ahmed, N. A. K; Lim, S. K.; Pandian, G. N.; Sugiyama, H.; Lee, C. Y.; Khoo, B. Y.; Chan, K. L.
Molecular Medicine Reports 2020, DOI: 10.3892/mmr.2020.11485.

450. Construction of a FRET System in a Double-Stranded DNA Using Fluorescent Thymidine and Cytidine Analogs
Hirashima, S.; Sugiyama, H.; Park, S.
J. Phys. Chem. B 2020, 124, 8794-8800.

449. Enhanced Nuclear Accumulation of Pyrrole-Imidazole Polyamides by Incorporation of the Tri-arginine Vector
Hidaka, T.; Tsubono, Y.; Hashiya, K.; Bando, T.; Pandian, G. N.; Sugiyama, H.
Chem. Comm. 2020, 56, 12371-12374.

448. Modular Quadruplex-Duplex Hybrids as Biomolecular Scaffolds for Asymmetric Michael Addition Reactions
Yum, J. H.; Sugiyama, H.; Park, S.
Org. Biomol. Chem. 2020, 18, 6812-6817.

447. Direct Observation of Dynamic Interactions between Orientation-Controlled Nucleosomes in a DNA Origami Frame
Feng, Y.; Hashiya, F.; Hidaka, K.; Sugiyama, H.; Endo, M.
Chem. Eur. J. 2020, 26, 15282-15289.

446. Design, Synthesis and Anti-cancer Activity of Pyrrole-Imidazole Polyamides through Target-downregulation of c-Kit Gene Expression
Zhang, M.; Liang, J.; Jiang, S-K.; Xu, L.; Wu, Y-L.; Awadasseid, A.; Zhao, X-Y.; Xiong, X-Q.; Sugiyama, H.; Zhang, W.
Eur. J. Med. Chem. 2020, 207, 112704.

445. DNA Alkylation of the RUNX-binding Sequence by CBI-PI Polyamides Conjugates
Maeda, R.; Ito, S.; Hashiya, K.; Bando, T.; Sugiyama, H.
Chem. Eur. J. 2020, 26, 14639-14644.

444. DNA Density-dependent Uptake of DNA Origami-based Two-or Three-dimensional Nanostructures by Immune Cells
Maezawa, T.; Ohtsuki, S.; Hidaka, K.; Sugiyama, H.; Endo, Takahashi, Y.; Takakura, Y.; Nishikawa, M.
Nanoscale 2020, 12, 14818-14824.

443. Development of Antibody-Oligonucleotide Complexes for Targeting Exosomal MicroRNA
Yamayoshi, A.; Oyama, S.; Kishimoto, Y.; Konishi, R.; Yamamoto, T.; Kobori, A.; Harada, H.; Ashihara, E.; Sugiyama, H.; Murakami, A.
Pharmaceutics 2020, 12, 545.

442. Control of Lipid Bilayer Phases of Cell-Sized Liposomes by Surface-Engineered Plasmonic Nanoparticles
Nobeyama, T.; Shigyou, K.; Nakatsuji, H.; Sugiyama, H.; Komura, N.; Ando, H.; Hamada, T.; Murakami, T.
Langmuir 2020, 36, 7741-7746.

441. Dynamic Stabilization of DNA Assembly by Using Pyrrole-Imidazole Polyamide
Ang, Y. S.; Bando, T.; Sugiyama, H.; Yung, L. Y. L.
ChemBioChem 2020, 21, 2912-2915.

440. X-ray Crystal Structure of a Cyclic-PIP–DNA Complex in the Reverse-binding Orientation
Abe, K.; Hirose, Y.; Eki, H.; Takeda, K.; Bando, T.; Endo, M.; Sugiyama, H.
J. Am. Chem. Soc. 2020, 142, 10544-10549.

439. A Photocaged DNA Nanocapsule for Delivery and Manipulation in Cells
Feng, Y.; Tohgasaki, T.; Shitomi, Y.; Sugiyama, H. Endo, M.
Methods in Enzymology 2020, 641, 329-342.

438. Duplex DNA is Weakened in Nanoconfinement
Jonchhe, S.; Pandey, S.; Karna, D.; Pokhrel, P.; Cui, Y.; Mishra, S.; Sugiyama, H.; Endo, M.; Mao, H.
J. Am. Chem. Soc. 2020, 142, 10042-10049.

437. Catalytic RNA Nano-objects Formed by Self-assembly of Group I Ribozyme Dimers Serving as Unit Structures
Kiyooka, R.; Akagi, J.; Sugiyama, H.; Endo, M. Matsumura, S.; Ikawa, Y.
J. Bioscience & Bioengineering 2020, 130, 253-259.

436. DNA Nanostructures for Targeted Antimicrobial Delivery
Mela, I.; Vallejo-Raminez, P. P.; Makarchuk, S.; Christie, G.; Bailey D.; Henderson, R. M.; Sugiyama, H, Endo, M.; Kaminski, C. F.
Angew. Chem. Int. Ed. 2020, 59, 12698-12702.

435. Telomeric Quadruplexes as Therapeutic Target
Asamitsu, S.; Shioda, N.; Sugiyama, H.
Stephen Needle (eds.), Quadruplex nucleic acids as targets for medicinal chemistry, Part 2 Quadruplex Targets in human and other organisms.
Elsevier 2020, 54, 77-99.

434. Histidine-conjugated DNA as a Biomolecular Depot for Metal Ions
Park, S.; Matsui, H.; Fukumoto, K.; Yum, J. H.; Sugiyama, H.
RSC Advances 2020, 10, 9717-9722.

433. Direct Observation and Analysis of TET-mediated Oxidation Processes in a DNA Origami Nanochip
Xing, X.; Sato, S., Wong, N-K.; Hidaka, K.; S.; Sugiyama, H.; Endo, M.
Nucleic Acids Research 2020, 48, 4041-4051.

432. N1-Methylpseudouridine Substitution Enhances the Performance of Synthetic mRNA Switches in Cells
Parr, C.; Wada, S.; Kotake, K.; Kameda, S.; Matsuura, S.; Sakashita, S.; Park, S.; Sugiyama, H.; Kuang, Y.; Saito, H.
Nucleic Acids Research 2020, 48, e35.

431. A Synthetic Transcription Factor Pair Mimic for Precise Recruitment of an Epigenetic Modifier to the Targeted DNA Locus
Zutao Yu, Z.; Ai, M; Samanta, S. K.; Hashiya, F.; Taniguchi, J.; Asamitsu, S.; Ikeda, S.; Hashiya, K.; Bando, T.; Pandian, G. N.; Isaacs, L.; Sugiyama, H.
Chem. Commun. 2020, 56, 2296-2299.

430. Targeted Suppression of Metastasis Regulatory Transcription Factor SOX2 in Various Cancer Cell Lines using a Sequence-specific Designer Pyrrole-imidazole Polyamide
Malinee, M.; Kumar, A.; Hidaka, T.; Horie, M.; Hasegawa, K.; Pandian, G. N.; Sugiyama, H.
Bioorg. Med. Chem. 2020, 28, 115248.

429. Advances in DNA Origami-Cell Interfaces
Mishra, S.; Feng, Y.; Endo, M.; Sugiyama, H.
ChemBioChem 2020, 21, 33-44.

428. Sequence-specific PI Polyamides Make It Possible to Regulate DNA Structure and Function
Bando, T.; Sugiyama, H.
Bull. Chem. Soc. J. 2020, 93, 205-215.