京都大学 物質－細胞統合システム拠点

Sugiyama Laboratory, Kyoto University

Publications :2021

2021 (Highlighted Articles Representing International Collaboration Project)

484. Photoswitchable Single-Stranded DNA-Peptide Coacervate Formation as a Dynamic System for Reaction Control
Wee, W. A.; Sugiyama, H.; Park, S.
iScience 2021, 24, 103455.

 483. Telomere-Specific Chromatin Capture using a Pyrrole–Imidazole Polyamide Probe for the Identification of Proteins and Non-Coding RNAs.
Ide, S.; Sasaki, A.; Kawamoto, Y.; Bando, T.; Sugiyama, H.; Maeshima, K.
Epigenetics & Chromatin 2021, 14, 46.

 482. Photo-controllable Phase Transition of Arylazopyrazole-conjugated Oligonucleotides
Hidaka,T.; Wee, W. A.; Yum, J. H.; Sugiyama, H.; Park, S.
Bioconjugate Chem, 2021, 32, 2129-2133.

 481. Characterization of a Conformation-restricted Amyloid β Peptide and Immunoreactivity of its Antibody in Human AD Brain
Kageyama, Y.; Irie, Y.; Matsushima, Y.; Segawa, T.; Bellier, J.-P.; Hidaka, K.; Sugiyama, H.; Kaneda, D.; Hashizume, Y.; Akatsu, H.; Miki, K.; Kita, A.; Walker, D. ; Irie, K.; Tooyama, I.
ACS Chemical Neuroscience, 2021, 12, 3418-3432.

 480. Integrated Analysis of Immune-related Gene Subtype and Immune Index for Immunotherapy in Clear Cell Renal Cell Carcinoma
Bai, D.; Chen, S.; Feng, H.; Yin, A.; Lu, J.; Ma, Y.; Sugiyama, H.
Pathol. Res. Pract., 2021, 225, 153557.

 479. Genomic Analysis Uncovers Prognostic and Immunogenic Characteristics of Ferroptosis for Clear Cell Renal Cell Carcinoma
Bai, D.; Feng, H.; Yang, J.; Yin, A.; Lin, X.; Qian, A.; Sugiyama, H.
Mol. Ther. Nucleic Acids, 2021, 25, 186-197.

 478. A Novel Method for Locating Nucleosomes by Exploiting 5-Bromouracil, Pyrene-Modified Histone, and Photoirradiation
Hashiya, F., Sugiyama, H.
Photomedicine and Photobiology, 2021, 42, 13-16.

 477. Flexible Assembly of Engineered Tetrahymena Ribozymes Forming Polygonal RNA Nanostructures with Catalytic Ability
Mori, Y.; Oi, H.; Suzuki, Y.; Hidaka, K.; Sugiyama, H.; Endo, M.; Matsumura, S.; Ikawa, Y.
ChemBioChem., 2021, 22, 2168-2176.

 476. Short Intrinsically Disordered Polypeptide-Oligonucleotide Conjugates for Programmed Self-assembly of Nanospheres with Temperature-dependent Size Controllability
 Wang, B.; Pan, R.; Zhu, W.; Xu, Y.; Tian, Y.; Endo, M.; Sugiyama, H.; Yang, Y.; Qian, X.
Soft Matter, 2021, 17, 1184-11886.
475. Tropylium Derivatives as New Entrants that Sence G-quadruplex Structures
Hori, D.; Yum, J. H.; Sugiyama, H.; Park, S.
Bull. Chem. Soc. J., 2021, 94, 1948-1953.

474. Impact of Reactive Oxygen Species and G-Quadruplexes in Telomeres and Mitochondria
Malinee, M.; Sugiyama, H.
Creative Complex Systems, Springer Book, Nishimura, K.; Murase, M.; Yoshimura, K. ed. Creative Complex Systems, 2021, 249-274.

 473. RUNX Inhibitor Suppresses Graft-versus-host Disease through Targeting RUNX-NFATC2 Axis
Kubota, H.; Masuda, T.; Noura, M.; Furuichi, K.; Matsuo, H.; Hirata, M.; Kataoka, T.; Hiramatsu, H.; Yasumi, T.; Nakahata, T.; Imai, Y.; Takita, J.; Adachi, S.; Sugiyama, H.; Kamikubo, Y.
eJHaem., 2021, 2, 449-458.

472. Discovery of Pyrrole-imidazole Polyamides as PD-L1 Expression Inhibitors and Their Anticancer Activity via Immune and Nonimmune Pathways
Wang, M.; Ma, X.; Zhou, K.; Mao, H.; Liu, J.; Xiong, X.; Zhao, X.; Narva, S.; Tanaka, Y.; Wu, Y.; Guo, C.; Sugiyama, H.; Zhang, W.
J. Med. Chem., 2021, 64, 6021-6036.
471. Non-invasive Regulation of Cellular Morphology Using a Photoswitchable Mechanical DNA Polymer
Sethi, S.; Hidaka, K.; Sugiyama, H.; Endo, M.
Angew. Chem. Int. Ed., 2021, 60, 20342-20349.

470. Construction of an Optically Controllable CRISPR-Cas9 System using a DNA Origami Nanostructure
Abe, K.; Sugiyama, H.; Endo, M.
Chem. Commun., 2021, 57, 5594-5596.

469. Sequence-Specific Control of Mitochondrial Gene Transcription using Programmable Synthetic Gene Switches called MITO-PIPs
Hidaka, T.; Sugiyama, H.; Pandian, G. N.
Methods Mol. Biol., 2021, 2275, 217-225.

468. Systematic Approach to DNA Aptamer Design Using Amino Acid-Nucleic Acid Hybrids (ANHs) Targeting Thrombin
Yum, J. H.; Ishizuka, T.; Fukumoto, K.; Hori, D.; Bao, H. L.; Xu, Y.; Sugiyama, H.; Park, S.
ACS Biomater. Sci. Eng., 2021, 7, 1338-1343.

467. Landscape of Immune Cell Infiltration in Clear Cell Renal Cell Carcinoma to Aid Immunotherapy
Bai, D.; Feng, H.; Yang, J.; Yin, A.; Qian, A.; Sugiyama, H.
Cancer Science, 2021, 112, 2126-2139.

466. HBD1 Protein with a Tandem Repeat of Two HMG Box Domains is a DNA Clip to Organize Chloroplast Nucleoids in Chlamydomonas Reinhardtii
Takusagawa, M.; Kobayashi, Y.; Fukao, Y.; Hidaka, K.; Endo, M.; Sugiyama, H.; Yamaji, T.; Kato, Y.; Miyakawa, I.; Misumi, O.; Shikanai, T.; Nishimura, Y.
Proc. Natl. Acad. Sci. USA., 2021, 118, 118 (20) e2021053118.

465. An RNA Triangle with Six Ribozyme Units can Promote a Trans-splicing Reaction through Trimerization of Unit Ribozyme Dimers.
Akagi, J.; Yamada, T.; Hidaka, K.; Fujita, Y.; Saito, H.; Sugiyama, H.; Endo, M.; Matsumura, S.; Ikawa, Y.
Applied Sciences, 2021, 11, 2583.

464. Synthesis and Application of a 19F-labeled Fluorescent Nucleoside as a Dual-mode Probe for i-Motif DNAs
Wee, W. A.; Yum, J. H.; Hirashima, S.; Sugiyama, H.; Park, S.
RSC Chem. Biol., 2021, 2, 876-882.

463. Nanoscopic Observation of a DNA Crystal Surface and Its Dynamic Formation and Degradation Using Atomic Force Microscopy
Eki, H.; Abe, K.; Sugiyama, H.; Endo, M.
Chem. Commun. 2021, 57, 1651-1654.

462. Application of DNA-Alkylating Pyrrole-Imidazole Polyamides for Cancer Treatment
Maeda, R.; Bando, T.; Sugiyama, H.
ChemBioChem., 2021, 22, 1538-1545.

461. Chemical Approaches to the Development of Artificial Transcription Factors Based on Pyrrole-Imidazole Polyamides
Hidaka, T.; Sugiyama, H.
Chemical Record, 2021, 21, 1374-1384.

460. Designing Biomimicking Synthetic Transcription Factors for Therapeutic Gene Modulation
Pandian, G. N.; Sugiyama, H.
Cell-Inspired Materials and Engineering, Springer Book., 2021, 135-161.

459. CGG Repeat RNA G-quadruplexes Interact with FMRpolyG to Cause Neuronal Dysfunction in Fragile X-related Tremor/ataxia Syndrome
Asamitsu, S.; Yabuki, Y.; Ikenoshita, S.; Kawakubo, K.; Kawasaki, M.; Usuki, S.; Nakayama, Y.; Adachi, K.; Kugoh, H.; Ishii, K.; Matsuura, T.; Nanba, E.; Sugiyama, H.; Fukunaga, K.; Shioda, N.
Science Advances 2021, 7, eabd9440.

458. Combined Use of Chemically Modified Nucleobases and Nanostructured DNA for Enhanced Immunostimulatory Activity of CpG Oligodeoxynucleotide
Araie, Y.; Ohtsuki, S.; Park, S.; Nagaoka, M.; Umemura, K.; Sugiyama, H.; Kusamori, K.; Takahashi, Y.; Takakura, Y.; Nishikawa, M.
Bioorg. Med. Chem. 2021, 29, 115864.

457. Evaluation of the DNA Alkylation Properties of a Chlorambucil-Conjugated Cyclic Pyrrole–Imidazole Polyamide
Hirose, Y.; Hashiya, K.; Bando, T.; Sugiyama, H.
Chem. Eur. J. 2021, 27, 2782-2788.

456. Photocontrolled DNA Origami Assembly using Two Photoswitches
Mishra, S.; Park, S.; Emura, T.; Hidaka, K.; Sugiyama, H.; Endo, M.
Chem. Eur. J. 2021, 27, 778-784.

455. Nucleosomes and Epigenetics from a Chemical Perspective
Feng, Y.; Endo, M.; Sugiyama, H.
ChemBioChem. 2021, 22, 595-612.

454. Targeted Epigenetic Modulation using a DNA-based Histone Deacetylase Inhibitor Enhances Cardiomyogenesis in Mouse Embryonic Stem Cells
Lee, J. A.; An, J.; Taniguchi, J.; Kashiwazaki, G.; Pandian, G. P.; Parveen, N.; Kang, T. M.; Sugiyama, H.; Kim K. K.
J. Cell. Phys. 2021, 236, 3946-3962.

453. Suppression of Malignant Rhabdoid Tumors through Chb-M’-mediated RUNX1 Inhibition
Daifu, T.; Mikami, M.; Hiramatsu, H.; Iwai, A.; Umeda, K.; Noura, M.; Kubota, H.; Matsuda, T.; Furuichi, K.; Takasaki, S.; Noguchi, Y.; Morita, K.; Bando, T.; Hirata, M.; Kataoka, T. R.; Nakahata, T.; Kuwahara, Y.; Iehara, T.; Hosoi, H.; Takita, J.; Sugiyama, H.; Adachi, S.; Kamikubo, Y.
Pediatric Blood & Cancer 2021, 68, e28789.