京都大学 物質−細胞統合システム拠点

Sugiyama Laboratory, Kyoto University

Publications :2015

2015 (Highlighted Articles Representing International Collaboration Project)

329. Induction of Stem-Cell-Derived Functional Neurons by NanoScript-Based Gene Repression
Patel, S.; Chueng, S. T. D.; Yin, P. T.; Dardir, K.; Song, Z. C.; Pasquale, N.; Kwan, K.; Sugiyama, H.; Lee, K. B.
Angew. Chem. Int. Ed. 2015, 54, 11983-11988.

328. Development of a Visible Nanothermometer with a Highly Emissive 2'-O-Methylated Guanosine Analogue
Yamaoto, S.; Park, S.; Sugiyama, H.
RSC Adv. 2015, 5, 104601-104605.

327. Efficient Amplification of Self-gelling Polypod-like Structured DNA by Rolling Circle Amplification and Enzymatic Digestion
Yata, T.; Takahashi, Y.; Tan, M. M.; Hidaka, K.; Sugiyama, H.; Endo, M.; Takakura, Y.; Nishikawa, M.
Sci. Rep. 2015, 5, 14979.

326. Water Revealed as Molecular Mirror When Measuring Low Concentrations of Sugar With Near Infrared Light
Bazar, G.; Kovacs, G.; Tanaka, M.; Furukawa, A.; Nagai, A.; Osawa, M; Itakura, Y; Sugiyama, H; Tsenkova, R.
Analytica Chimica Acta. 2015, 896, 52-62.

325. Single-Molecule Manipulation of the Duplex Formation and Dissociation at the G-Quadruplex/i-Motif Site in the DNA Nanostructure
Endo, M.; Xing, X. W.; Zhou, X.; Tomoko, E.; Hidaka, K.; Tuesuwan,; B. Sugiyama, H.
ACS Nano. 2015, 9, 9922-9929.

324. Direct Visualization of Walking Motions of Photocontrolled Nanomachine on the DNA Nanostructure
Yang, Y.; Endo, M.; Goetzfied, M. A.; Hidaka, K.; You, M. X.; Tan, W. H.; Sugiyama, H.
Nano Lett. 2015, 15, 6672-6676.

323. Inducing Stem Cell Myogenesis Using NanoScript
Patel, S.; Yin, T. P.; Sugiyama, H.; Lee, K. B.
ACS Nano. 2015, 9, 6909-6917.

322. Atomic Force Microscopy Analysis of Orientation and Bending of Oligodeoxynucleotides in Polypod-like Structured DNA
Shiomi, T.; Tan, M. M.; Takahashi, N.; Endo, M.; Emura, T.; Hidaka, K.; Sugiyama, H.; Takahashi, Y.; Takakura, Y.; Nishikawa, M.

Nano. Research. 2015, 8, 3764-3771.

321. A Novel Detection Technique of Polyamide Binding Sites by Photo-Induced Electron Transfer in BrU Substituted DNA
Saha, A.; Hashiya, F.; Kizaki, S.; Asamitsu, S.; Hashiya, K.; Bando, T.; Sugiyama, H.

Chem. Commun. 2015, 45, 14485-14488.

320. Measuring Chloride in Live Cells
Endo, M.; Sugiyama, H.

Nat. Nanotechnol. 2015, 10, 569-570.

319. Lipid-bilayer-assisted Two-dimensional Self-assembly of DNA Origami Nanostructures
Suzuki, Y.; Endo, M.; Sugiyama, H.
Nat. Commun. 2015, 6, 8052.

318. Development of DNA Metalloenzymes Using a Rational Design Approach and Application in the Asymmetric Diels-Alder Reaction
Park, S.; Okamura, I.; Sakashita, S.; Yum, J. H.; Chiranjit, A.; Gao, L.; Sugiyama, H.
ACS Catal. 2015, 5, 4708-4712.

317. Selective Targeting of the KRAS Codon 12 Mutation Sequence by Pyrrole-Imidazole Polyamide seco-CBI Conjugates
Taylor, R. D.; Chandran, A.; Kashiwazaki, G.; Hashiya, K.; Bando, T.; Nagase, H.; Sugiyama, H.
Chem. Eur. J. 2015, 21, 14996-15003.

316. Optimal Arrangement of Four Short DNA Strands for Delivery of Immunostimulator Nucleic Acids to Immune Cells
Ohtsuki, S.; Matsuzaki, N.; Mohri, K.; Endo, M.; Emura, T.; Hidaka, K.; Sugiyama, H.; Takahashi, Y.; Ishiyama, K.; Kadowaki, N.; Takakura, Y.; Nishikawa, M.
Nucleic Acid Therapeutics. 2015, 5, 4708-4712.

315. Linking Two DNA Duplexes with a Rigid Linker for DNA Nanotechnology
Tashiro, R.; Iwamoto, M.; Morinaga, H.; Emura, T.; Hidaka, K.; Endo, M.; Sugiyama, H.
Nucleic Acids Res. 2015, 25, 245-253.

314. Folding RNA-Protein Complex into Designed Nanostructures
Shibata, T.; Suzuki, Y.; Sugiyama, H.; Endo, M.; Saito, H.
Springer Book. Methods in Molecular Biology. 2015, 1316, 169-179.

313. Single-Molecule Visualization of the Activity of a Zb2+ Dependent
Endo, M.; Takeuchi, Y.; Suzuki, Y.; Emura, T.; Hidaka, K.; Wang, F.; Willner, I.; Sugiyama, H.
Angew. Chem. Int. Ed. 2015, 54, 10550-10554.

312. Detection of UV-induced Cyclobutane Primidine Dimers by Near-infared Spectroscopy and Aquaphotomics
Goto, N.; Bazar, G.; Kovacs, Z.; Kunusada, M.; Morita, H.; Kizaki, .S; Sugiyam, H.; Tesenkova, R.; Nishigori, C.
Sci. Rep. 2015, 5, 11808.

311. Studying RNAP-promoter Interactions Using Atomic Force Microscopy
Suzuki, Y.; Endo, M.; Sugiyama, H.
Methods. 2015, 86, 4-9.

310. A Synthetic DNA-Binding Domain Guides Distinct Chromatin-Modifying Small Molecules to Activate an Identical Gene Network
Han, L.; Pandian, G, N.; Chandran, A.; Sato, S.; Taniguchi, J.; Kashiwazaki, G.; Sawatani, Y.; Hashiya, K.; Bando, T.; Xu, Y.; Qian, X,; Sugiyama, H.
Angew. Chem. Int. Ed. 2015, 54, 8700-8703.

309. A Synthetic Transcriptional Activator of Genes Associated with Retina in Human Dermal Fibroblasts
Syed, J.; Chandran, A.; Pandian, G, N.; Taniguchi, J.; Sato, S.; Hashiya, K.; Kashiwazaki, G.; Bando, T.; Sugiyama, H.
ChemBioChem. 2015, 16, 1497-1501.

308. Photoreactivity of the Linker Region of Two Consecutive G-quadruplexes Formed by Human Telomeric DNA
Li, Y; Sugiyama, H.
Chem. Commun. 2015, 51, 8861-8864.

307. Mimicking Membrane-Related Biological Events by DNA Origami Nanotechnology
Suzuki, Y.; Endo, M.; Sugiyama, H.
ACS. Nano. 2015, 9, 3418-3420.

306. Small Molecule Binding to a G-hairpin and a Griplex: A New Insight in Anticancer Drug Design Targeting G-rich Regions
Rajendran, A.; Endo, M.; Hidaka, K.; Teulade-Fichou, M.; Mergny, J, L.; Sugiyama, H.
Chem. Commun. 2015, 9, 3418-3420.

305. Preclinical Study of Novel Gene Silencer Pyrrole-Imidazole Polyamide Targeting Human TGF-β1 Promoter for Hypertrophic Scars in a Common Marmoset Primate Model
Igarashi, J.; Fukuda, N.; Inoue, T.; Nakai, S.; Saito, K.; Fujiwara, K.; Matsuda, H.; Ueno, T.; Matsumoto, Y.; Watanabe, T.; Nagase, H.; Bando, T.; Sugiyama, H.; Itoh, T.; Soma, M.
PLOS. ONE. 2015, 10, e0125295.

304. Integrating Epigenetic Modulators into NanoScript for Enhances Chondrogenesis of Stem Cells
Patel, S.; Pongkulapa, T.; Yin, P.; Pandian, G, N.; Rathnam, C.; Bando, T.; Vaijayanthi, T.; Sugiyama, H.; Lee, K, B.
J. Am. Chem. Soc. 2015, 137, 4598-4601.

303. Self-Assembling DNA Dendrimer for Effective Delivery of Immunostimulatory CpG DNA to Immune Cells
Mohri, K.; Kusuki, Eri.; Ohtsuki, S.; Takahashi, N.; Endo, M.; Hidaka, K.; Sugiyama, H.; Takahashi, Y.; Takakura, Y.; Nishikawa, M.
Biomacromolecules. 2015, 16, 1095-1101.

302. Inhibition of KRAS Codon 12 Mutants Using a Novel DNA-alkylating Pyrrole-imidazole Polyamide Conjugate
Hiraoka, K.; Inoue, T.; Taylor, R. D.; Watanabe, T.; Koshikawa, N.; Yoda, H.; Shinohara, K.; Takatori, A.; Sugimoto, K.; Maru, Y.; Denda, T.; Fujiwara, K.; Balmain, A.; Ozaki, T.; Bando, T.; Sugiyama, H.; Nagase, H.
Nat. Commun. 2015, 6, 6706.

301. Tandem Trimer Pyrrole-Imidazole Polyamide Probes Targeting 18 Base Pairs in Human Telomere Sequence
Kawamoto, Y.; Sasaki, A.; Hashiya, K.; Ide, S; Bando, T.; Maeshima, K; Sugiyama, H.
Chem. Sci. 2015, 6, 2307-2312.

300. Rational Design of Specific Binding Hairpin Py-Im Polyamides Targeting Human Telomere Sequences
Guo, C. X .; Kawamoto, Y.; Asamitsu, S.; Sawatani, Y.; Hashiya, K.; Bando, T.; Sugiyama, H.
Bioorg. Med. Chem. 2015, 23, 855-860.

299. Advancing Small-Molecule-Based Chemical Biology with Next-Generation Sequencing Technologies
Chandran, A.; Kizaki, S.; Bando, T.; Pandian, G. N.; Sugiyama, H.
ChemBioChem. 2015, 16, 20-38.

298. Synthetic Strategies to Identify and Regulate Noncoding RNAs
Pandian, G. N.; Syed, J.; Sugiyama, H.
Long Noncoding RNAs: Structure and Function. Springer Book.