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Organization

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Coordinator Group

Project Leader, A01 Group Leader

TERAZIMA, Masahide

Kyoto Univ.

Secretary General, A02 Group Leader

KATAOKA, Mikio

NAIST

A03 Group Leader

UEOKA, Ryuichi

Sojo Univ.

Member

KATO, Koichi

OIIB

Member

OKAMOTO, Yuko

Nagoya Univ.

Member

HOHSAKA, Takahiro

JAIST

Member

HIRATA, Fumio

Ritsumeikan Univ.

Member

KUWAJIMA, Kunihiro

OIIB

Advisers

KITAGAWA,Teizo

Univ. of Hyogo

NAKAHARA, Masaru

Kyoto Univ.

SAKAKI, Shigeyoshi

Kyoto Univ.

MILLER, R. J. Dwayne

Centre for Free Electron Laser Science, Germany
University of Toronto, Canada

Nominated Researchers

TERAZIMA, Masahide

Kyoto Univ.

A01

Development of time-resolved methods for detections of energy and structural fluctuations, and revealing relationship between fluctuation and reaction mechanism

KATO, Koichi

OIIB

A01

NMR detection of conformational fluctuations of proteins and glycoconjugates for exploration of their correlations with biological functions

OKAMOTO, Yuko

Nagoya Univ.

A01

Development of molecular simulation algorithms for enhancing structural fluctuations and for accurate free-energy calculations

KATAOKA, Mikio

NAIST

A02

Development of model systems for intrinsically disordered protein and understanding of the role of fluctuation on molecular recognition and folding

HOHSAKA, Takahiro

JAIST

A02

Study of protein fluctuations by introducing nonnatural amino acids

UEOKA, Ryuichi

Sojo Univ.

A03

Antitumor mechanism in molecular model with relation to fluctuation of tumor cell membranes and liposomes

HIRATA, Fumio

Ritsumeikan Univ.

A03

Theoretical Study on Conjugated Dynamics of Protein and Solvent

KUWAJIMA, Kunihiro

OIIB

A03

Structural fluctuations and folding-mediating functions of the chaperonin

Open-type Researchers

HAYASHI, Kumiko

Tohoku Univ.

A01

Innovation of new theory of non-equilibrium statistical mechanics and its application to single molecule experiments

IMAMOTO, Yasushi

Kyoto Univ.

A01

Detection of the structural fluctuation essential for the selective interaction of proteins

ISHII, Kunihiko

RIKEN

A01

Application of advanced fluorescence correlation spectroscopy to detection of biomolecular fluctuations

KAWAKAMI, Masaru

JAIST

A01

Exploring the conformational energy landscape and detection of the protein fluctuation of myoglobin by single molecule mechanical unfolding and refolding experiments

KITAHARA, Ryo

Ritsumeikan Univ.

A01

Structure and function studies for high-energy states of proteins

KITAO, Akio

Univ. of Tokyo

A01

Development of mode coupling analysis method relevant to protein complex formation and dissociation

NISHIMURA, Chiaki

Teikyo Heisei Univ.

A01

Development of new NMR strategy for the analysis of the intrinsically disordered region in the amyloid protein, and understanding of the role of the fluctuated motion in protein on the amyloid formation including the different type of the morphological formation

SAKURAI, Kazumasa

Osaka Univ.

A01

Identification of common properties of the precursor state for the native state and amyloid fibril of protein

SATO, Hirofumi

Kyoto Univ.

A01

Statistical mechanics and dynamics of fluctuation based on integral equation theory

SEKIGUCHI, Hiroshi

JASRI

A01

Development of the high-speed single molecular technique to track internal motion of membrane proteins

TAKADA, Shoji

Kyoto Univ.

A01

Theoretical study of large-amplitude fluctuations of proteins: From conformational change pathway to disorders

TAKAHASHI, Satoshi

Tohoku Univ.

A01

Single molecule detection of the fast conformational fluctuations and the in-cell stabilities of proteins

YAMAMURA, Yasuhisa

Univ. of Tsukuba

A01

Thermodynamic approach to detection of fluctuation of pseudo-biomembrane system

ARAI, Munehito

Univ. of Tokyo

A02

Controlling fluctuation of an intrinsically disordered protein by mutanome analysis

MIZUGUCHI, Mineyuki

Univ. of Toyama

A02

Fluctuation and function of the mental retardation associated protein, PQBP-1

TATE, Shin-ichi

Hiroshima Univ.

A02

NMR study on the transient-folding of an intrinsically disordered element

TERAUCHI, Kazuki

Ritsumeikan Univ.

A02

Regulation of a fluctuant protein with a period of 24 hours

YUASA, Junpei

NAIST

A02

Detection and regulation of fluctuation in photoreceptor proteins by probe molecules

AIZAWA, Tomoyasu

Hokkaido Univ.

A03

Analysis of fluctuations in molecular recognition of a novel tandem repeat DNA-binding domain

DEWA, Takehisa

NIT

A03

Functional analysis of polyamine-lipid/nucleic acid complex (Lipoplex) for nucleic acid delivery: Relationship between metamorphosis of lipoplex and its function

HAMADA, Daizo

Kobe Univ.

A03

Conformational fluctuations in proteins that determine the conformational and physicochemical properties of cytotoxic protein oligomers

HAYASHI, Shigehiko

Kyoto Univ.

A03

Molecular mechanism of pKa regulation in protein functions

HIROTA, Shun

NAIST

A03

Formation of oligomeric cytochrome c by fluctuation and its function

IINO, Ryota

Univ. of Tokyo

A03

Development of an ultra-high speed orientation imaging system for the investigation of conformational fluctuation of motor proteins

INOBE, Tomonao

Univ. of Toyama

A03

Fluctuation-mediated substrate recognition by the proteasome

MATSUMOTO, Yoko

Sojo Univ.

A03

Clinical applications in relation to apoptosis and membrane fluctuation

MOTOJIMA, Fumihiro

Kyoto Sangyo Univ.

A03

The analysis of the restricted fluctuation of polypeptide in the chaperonin-assisted folding

NAKANO, Minoru

Univ. of Toyama

A03

Clarification of lipid–protein interactions relevant to disruption of membrane asymmetry by neutron scattering

NOGUCHI, Hiroshi

Univ. of Tokyo

A03

Fusion dynamics of biomembranes

OHHASHI, Yumiko

RIKEN

A03

Elucidation of relationship between protein fluctuation and amyloid polymorphism

OKADA, Seiji

Kumamoto Univ.

A03

Regulation of normal and malignant hematopoiesis by membrane fluctuation

OSAWA, Masanori

Univ. of Tokyo

A03

NMR studies on dynamics of voltage-gated ion channels and the underlying structural mechanisms for their functions

SUZUKI, Motoshi

Nagoya Univ.

A03

A bidirectional research to reveal the relationship between genetic fluctuation and lung cancer

TAKEUCHI, Koh

AIST

A03

NMR analysis of the functional coupling between structural fluctuation and drug transportation in prokaryotic multi-drug transporter

TOTANI, Kiichiro

Seikei Univ.

A03

Glycan processing analysis under biomimetic artificial fluctuation environments

Collaborators

IDE, Toru

GPI

Structure-activity relationship study of ion-channel proteins by single-molecule analyses

IMANISHI, Miki

Kyoto Univ.

Creation and functional analysis of artificial zinc finger proteins

ISHIMORI, Koichiro

Hokkaido Univ.

Quantitative analysis of the structural fluctuation in protein studied with florescence spectroscopy under high pressure

IWATA, Koichi

Gakushuin Univ.

Examination of structure and function of lipid bilayer membrane with spectroscopic methods

KURODA, Reiko

Tokyo Univ. of Science

The molecular dynamics of proteins related to amyloidosis

KURODA, Yutaka

TUAT

Amino acid contribution to protein solubility analyzed using short peptide tags. - Influence of vibration on protein aggregation-

MAJIMA, Tetsuro

Osaka Univ.

Charge Transfer in DNA

MATSUSHITA, Taku

Sojo Univ.

Molecular Scientific Study on G-quadruplex fluctuations and functions of telomeric DNA

OIKI, Shigetoshi

Univ. of Fukui

Dynamics of the structure-function of ion channels

OKAMURA, Emiko

Himeji Dokkyo Univ.

Multinuclear dynamic NMR of peptide transfer from water to soft lipid membranes

SASAHARA, Kenji

Kobe Univ.

Analysis of amyloid aggregation affecting dynamic properties of lipid membranes

SONOYAMA, Masashi

Gunma Univ.

Effect of partial fluorination in the acyl chain of phosphatidylcholine on structure and function of integral membrane proteins incorporated into lipid bilayer

TERO, Ryugo

TUT

Structural fluctuation and reactivity of lipid assemblies in lipid bilayer membranes

YAMAMOTO, Naoki

Kobe Univ.

Low-frequency dynamics of proteins studied by terahertz time-domain spectroscopy

YANO, Yohko F.

Kinki Univ.

Development of X-ray reflection system for investigating the structural fluctuation at interfaces and understanding of the interaction between a protein and an interface