DNA Nanotechnology Group

発表論文SERVICE&PRODUCTS

2021   

  • CreHBD1 protein with a tandem repeat of two HMG box domains is a DNA clip to organize chloroplast nucleoids.
    M. Takusagawa, Y. Kobayashi, Y. Fukao, K. Hidaka, M. Endo, H. Sugiyama, T. Hamaji, I. Miyakawa, O. Misumi, T. Shikanai, Y. Nishimura,
    Proc. Natl. Acad. Sci. USA, 118, in press (2021).
  • Nanoscopic observation of DNA crystal surface and its dynamic formation and degradation using atomic force microscopy.
    H. Eki, K. Abe, H. Sugiyama, M. Endo,
    Chem. Commun. 57, 1651-1654 (2021).
  • Photocontrolled DNA origami assembly using two photoswitches.
    S. Mishra S. Park, T. Emura, K. Hidaka, H. Sugiyama, M. Endo,
    Chem. Eur. J. 27, 778-784 (2021).
  • Micro-homology intermediates: RecA’s transient sampling revealed at the single molecule level.
    A. J. Lee, M. Endo, J. Hobbs, A. Davies, C. Walti,
    Nucleic Acids Res. 49, 1426–1435 (2021).
  • Short Intrinsically Disordered Polypeptide-oligonucleotide Conjugates for Programmed Self-assembly of Nanospheres with Temperature-dependent Size Controllability.
    B. Wang, R. Pan, W. Zhu, Y. Xu, Y. Tian, M. Endo, H. Sugiyama, Y. Yang, X. Qian,
    Soft Matter, 17, 1184-1188 (2021).
  • An RNA triangle with six ribozyme units can promote a trans-splicing reaction through trimerization of unit ribozyme dimers.
    J. Akagi, T. Yamada , K. Hidaka, Y. Fujita, H.e Saito, H. Sugiyama, M. Endo, S. Matsumura, Y. Ikawa,
    Appl. Sci. in press (2021).
  • Nucleosomes and epigenetics from a chemical perspective.
    Y. Feng, M. Endo, H. Sugiyama,
    ChemBioChem. 22, 595–612 (2021).
  • DNA nanotechnology to disclose molecular events at the nanoscale and mesoscale levels.
    M. Endo,
    Cell-Inspired Materials and Engineering (Dan O. Wang, Daniel Packwood Eds.), Springer Nature, in press (2021).
  • Two-dimensional DNA origami lattices assembled on lipid bilayer membranes.
    Y. Suzuki, H. Sugiyama, M. Endo,
    DNA Origami: Methods and Protocols (Julián Valero Ed.), Methods in Molecular Biology , Springer Nature, in press (2021).

2020   

  • Direct observation of dynamic interactions between orientation-controlled nucleosomes in a DNA origami frame.
    Y. Feng, F. Hashiya, K. Hidaka, H. Sugiyama, M. Endo,
    Chem. Eur. J. 26, 15282−15289 (2020).
  • X-ray crystal structure of a cyclic-PIP–DNA complex in the reverse-binding orientation.
    K. Abe, Y. Hirose, H. Eki, K. Takeda, T. Bando, M. Endo, H. Sugiyama,
    J. Am. Chem. Soc. 142, 10544−10549 (2020).
  • Duplex DNA is Weakened in Nanoconfinement.
    S. Jonchhe, S. Pandey, D. Karna, P. Pokhrel, S. Mishra, H. Sugiyama, M. Endo, H. Mao,
    J. Am. Chem. Soc. 142, 10042−10049 (2020).
  • DNA nanostructures as a tool for targeted antimicrobial delivery.
    I. Mela, P. Vallejo-Ramirez, S. Makarchuk, G. Christie, D. Bailey, R. Henderson, H. Sugiyama, M. Endo, C. Kaminski,
    Angew. Chem. Int. Ed. 59, 12698 –12702 (2020).
  • Direct Observation And Analysis of TET-mediated Oxidation Process in a DNA Origami Nanochip.
    X. Xing, S. Sato, N. Wong, K. Hidaka, H. Sugiyama, M. Endo,
    Nucleic Acids Res. 48, 4041–4051 (2020).
  • DNA Density-dependent Uptake of DNA Origami-based Two-or Three-dimensional Nanostructures by Immune Cells.
    T. Maezawa, S. Ohtsuki, K. Hidaka, H. Sugiyama, M. Endo, Y. Takahashi, Y. Takakura, M. Nishikawa,
    Nanoscale, 12, 14818-14824 (2020).
  • Catalytic RNA nano-objects formed by self-assembly of group I ribozyme dimers serving as unit structures.
    R. Kiyooka, J. Akagi, K. Hidaka, H. Sugiyama, M. Endo, S. Matsumura, Y. Ikawa,
    J. Biosci. Bioeng. 130, 253-259 (2020).
  • Advances in DNA Origami-Cell interfaces.
    S. Mishra, Y. Feng, M. Endo, H. Sugiyama,
    ChemBioChem. 21, 33-44 (2020).
  • A Photocaged DNA Nanocapsule for for delivery and manipulation in cells.
    Y. Feng, T. Tohgasaki, Y. Shitomi, H. Sugiyama, M. Endo,
    Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Chemical, Optical and Bioorthogonal Methods (David M. Chenoweth Ed.),
    Methods in Enzymology, Volume 641, 2020, Pages 329-342. (invited)

2019   

  • Direct observation and analysis of the dynamics of the photoresponsive transcription factor GAL4.
    G. Raghavan, K. Hidaka, H. Sugiyama, M. Endo,
    Angew. Chem. Int. Ed. 58, 7626-7630 (2019).
  • DNA origami nanoplate-based emulsion with designed nanopore function.
    D. Ishikawa, Y. Suzuki, C. Kurokawa, M. Ohara, M. Tsuchiya, M. Morita, M. Yanagisawa, M. Endo, R. Kawano, M. Takinoue,
    Angew. Chem. Int. Ed. 58, 15299-15303 (2019).
  • A Photocaged DNA Nanocapsule for Controlled Unlocking and Opening inside the Cell.
    T. Tohgasaki, Y. Shitomi, Y. Feng, S. Honna, T. Emura, K. Hidaka, H. Sugiyama, M. Endo,
    Bioconjugate Chem. 30, 1860-1863 (2019).
  • Direct observation of the double-stranded DNA formation through metal ion-mediated base pairing in the nanoscale structure.
    X. Xing, Y. Feng, Z. Yu, K. Hidaka, F. Liu, A. Ono, H. Sugiyama, M. Endo,
    Chem. Eur. J. 25, 1446-1450 (2019).
  • Programming Rotary Motions with a Hexagonal DNA Nanomachine.
    Y. Yang, S. Zhang, S. Yao, R. Pan, K. Hidaka, T. Emura, C. Fan, H. Sugiyama, Y. Xu, M. Endo, X. Qian,
    Chem. Eur. J. 25, 5158-5162 (2019).
  • Effects of Physical Damage in the Intermediate Phase on the Progression of Amyloid bFibrillization.
    R. Tashiro, H. Taguchi, K. Hidaka, M. Endo, H. Sugiyama,
    Chem. Asian J. 14, 4140-4145 (2019).
  • Translation-dependent unwinding of stem-loops by UPF1 licenses Regnase-1 to degrade inflammatory mRNAs.
    T. Mino, N. Iwai, M. Endo, K. Inoue, K. Akaki, F. Hia, T. Uehata, T. Emura, K. Hidaka, Y. Suzuki, D. M. Standley, M. Okada-Hatakeyama, S. Ohno, H. Sugiyama, A. Yamashita, O. Takeuchi,
    Nucleic Acids Res. 47, 8838–8859 (2019).
  • Folding of Single-stranded Circular DNA into Rigid Rectangular DNA Accelerates its Cellular Uptake.
    S. Ohtsuki, Y. Shiba, T. Maezawa, K. Hidaka, H. Sugiyama, M. Endo, Y. Takahashi, Y. Takakura, M. Nishikawa,
    Nanoscale, 11, 23416-23422 (2019).
  • AFM-based single-molecule observation of the conformational changes of DNA structures.
    M. Endo,
    Methods, 169, 3-10 (2019). (invited)
  • Colloidal Plasmonic DNA-Origami with Photo-Switchable Chirality in Liquid Crystals.
    Q. Liu, A. Kuzyk, M. Endo, I. Smalyukh,
    Optics Lett. 44, 2831-2834 (2019).
  • Using DNA Origami to Contextualize Direct Observations of Enzymes in Action.
    A. Lee, M. Endo, J. Hobbs, C. Walti,
    Imaging & Microscopy, 21, 42-44 (2019).
  • Oligomerization of a modular ribozyme assembly of which is controlled by a programmable RNA–RNA interface between two structural modules.
    R. Tsuruga, N. Uehara, Y. Suzuki, H. Furuta, H. Sugiyama, M. Endo, S. Matsumura, Y. Ikawa,
    J. Biosci. Bioeng. 128, 410-415 (2019).
  • Direct observation of the formation and dissociation of double-stranded DNA containing G-quadruplex/i-motif sequences in the DNA origami frame using high-speed AFM.
    M. Endo, X. Xing, H. Sugiyama,
    G-quadruplex Nucleic Acids: Methods and Protocols, (Danzhou Yang and Clement Lin Eds.),
    Methods in Molecular Biology, Springer Nature, vol. 2035, 299-308 (2019).

2018   

  • Decreased water activity in nanoconfinement contributes to the folding of G-quadruplex and i-motif structures.
    S. Jonchhe, S. Pandey, T. Emura, K. Hidaka, M. A Hossain, P Shrestha, H. Sugiyama, M. Endo, H. Mao,
    Proc. Natl. Acad. Sci. USA 115, 9539-9544 (2018).
  • Construction of integrated gene logic-chip.
    T. Masubuchi, M. Endo, R. Iizuka, A. Iguchi, D. H. Yoon, T. Sekiguchi, H. Qi, R. Iinuma, Y. Miyazono, S. Shoji, T. Funatsu, H. Sugiyama, Y. Harada, T. Ueda, H. Tadakuma,
    Nature Nanotechnology, 13, 933-940 (2018).
  • Complexing DNA origami frameworks through sequential self-assembly based on directed docking.
    Y. Suzuki, H. Sugiyama, M. Endo,
    Angew. Chem. Int. Ed. 57, 7061-7065 (2018).
  • DNA Origami Scaffolds as Templates for Functional Tetrameric Kir3 K+ Channels.
    T. Kurokawa, S. Kiyonaka, E. Nakata, M. Endo, S. Koyama, E. Mori, N. H. Tran, H. Dinh, Y. Suzuki, K. Hidaka, M. Kawata, C. Sato, H. Sugiyama, T. Morii, Y. Mori,
    Angew. Chem. Int. Ed. 57, 2586-2591 (2018).
  • Direct Single-Molecule Observation of Mode and Geometry of RecA-Mediated Homology Search.
    A. Lee, M. Endo, J. Hobbs, C. Wälti,
    ACS Nano, 12, 272-278 (2018).
  • Triggering Nucleic Acid Nanostructure Assembly By Conditional Kissing Interactions.
    L. Azéma, S. Bonnet-Salomon, M. Endo, Y. Takeuchi, G. Durand, T. Emura, K. Hidaka, E. Dausse, H. Sugiyama, J.-J. Toulmé,
    Nucleic Acids Res. 46, 1052-1058 (2018).
  • Environment-dependent Self-assembly of DNA Origami Lattices on Phase-separated Lipid Membranes.
    Y. Sato, M. Endo, M. Morita, M. Takinoue, H. Sugiyama, S. Murata, S. M. Nomura, Y. Suzuki,
    Advanced Materials Interfaces, 5, 1800437 (2018).
  • DNA origami nanomachines.
    M. Endo, H. Sugiyama,
    Molecules, 23, 1766 (2018). (invited)
  • Direct observation of dynamic movement of DNA molecules in DNA origami imaged using high-speed AFM.
    M. Endo, H. Sugiyama,
    Nanoscale Imaging: Methods and Protocols, (Yuri L. Lyubchenko Ed.),
    Methods in Molecular Biology, Springer Nature, vol. 1814, pp 213-224 (2018). (invited)


2017   

  • Single-Molecule Observation of The Photoregulated Conformational Dynamics of DNA Origami Nanoscissors.
    E. M. Willner, Y. Kamada, Y. Suzuki, T. Emura, K. Hidaka, H. Dietz, H. Sugiyama, M. Endo,
    Angew. Chem. Int. Ed. 56, 15324-15328 (2017).
  • Holliday-junction resolvases mediate chloroplast nucleoid segregation.
    Y. Kobayashi, O. Misumi, M. Odahara, K. Ishibashi, M. Hirono, K. Hidaka, M. Endo, H. Sugiyama, H. Iwasaki, T. Kuroiwa, T. Shikanai, Y. Nishimura,
    Science, 356, 631-634 (2017).
  • Confined Space Facilitates G-quadruplex Formation.
    P. Shrestha, S. Jonchhe, T. Emura, K. Hidaka, M. Endo, H. Sugiyama, H. Mao,
    Nature Nanotechnology, 12, 582–588 (2017).
  • Protein-driven RNA nanostructured devices that function in vitro and control mammalian cell fate.
    T. Shibata, Y. Fujita, H. Ohno, Y. Suzuki, K. Hayashi, K. R. Komatsu, S. Kawasaki, K. Hidaka, S. Yonehara, H. Sugiyama, M. Endo, H. Saito,
    Nature Communications, 8, 540 (2017).
  • A Photoregulated DNA-Based Rotary System And Direct Observation of Its Rotational Movement.
    Y. Yang, R. Tashiro, Y. Suzuki, T. Emura, K. Hidaka, H. Sugiyama, M. Endo,
    Chem. Eur. J. 23, 3979-3985 (2017).
  • High-Resolution Imaging of a Single Gliding Protofilament of Tubulins by HS-AFM.
    J. J. Keya, D. Inoue, Y. Suzuki, T. Kozai, N. Kodera, T. Uchihashi, A. Md. R. Kabir, M. Endo, K.Sada, A. Kakugo,
    Sci. Rep. 7, 6166 (2017).
  • Programmable formation of catalytic RNA triangles and squares by assembling modular RNA enzymes.
    H. Oi, D. Fujita, Y. Suzuki, H. Sugiyama, M. Endo, S. Matsumura, Y. Ikawa,
    J. Biochem. 161, 451-462 (2017).

2016   

  • Torsional Constraints of DNA Substrates Impact Cas9 Cleavage.
    M. H. Räz, K. Hidaka, S. J. Sturla, H. Sugiyama, M. Endo,
    J. Am. Chem. Soc. 138, 13842-13845 (2016).
  • Triple Helix Formation in a Topologically Controlled DNA Nanosystem.
    Y. Yamagata, T. Emura, K. Hidaka, H. Sugiyama, M. Endo,
    Chem. Eur. J. 22, 5494-5498 (2016).
  • Mechanical Properties of DNA Origami Nanoassemblies are Determined by Holliday Junction Mechanophores.
    P. Shrestha, T. Emura, D. Koirala, K. Hidaka, W. Maximuck, M. Endo, H. Sugiyama, H. Mao,
    Nucleic Acids Res. 44, 6574-6582 (2016).
  • Examining cooperative binding of Sox2 on DC5 regulatory element upon complex formation with Pax6 through excess electron transfer assay.
    A. Saha, S. Kizaki, D. De, M. Endo, K. K. Kim, H. Sugiyama,
    Nucleic Acids Res. 44, e125 (2016).
  • A light-driven 3D plasmonic nanosystem that translates molecular motion into reversible chiroptical function.
    A. Kuzyk, Y. Yang, X. Duan, S. Stoll, A. O. Govorov, H. Sugiyama, M. Endo, N. Liu,
    Nature Communications, 7, 10591 (2016).
  • Single-molecule observations of RNA-RNA kissing interactions in a DNA nanostructure.
    Y. Takeuchi, M. Endo, Y. Suzuki, K. Hidaka, G. Durand, E. Dausse, J.-J. Toulmé, H. Sugiyama,
    Biomater. Sci. 4, 130-135 (2016).
  • Self-assembling DNA hydrogel-based delivery of immunoinhibitory nucleic acids to immune cells.
    Y. Nishida, S. Ohtsuki, Y. Araie, Y. Umeki, M. Endo, T. Emura, K. Hidaka, H. Sugiyama, Y. Takahashi, Y. Takakura, M. Nishikawa,
    Nanomedicine, 12, 123-130 (2016).
  • Single-Molecule Visualization of Biomolecules in the designed DNA Origami Nanostructures Using High-Speed Atomic Force Microscopy.
    M. Endo, RNA Technologies (V. A. Erdmann, S. Jurga, J. Barciszewski Eds.) Modified Nucleic Acids in Biology and Medicine, Springer Nature, Volume 7, pp 403-427 (2016).

2015   

  • Single-Molecule Manipulation of the Duplex Formation and Dissociation at the G-Quadruplex/i-Motif Site in the DNA Nanostructure.
    M. Endo, X. Xing, X. Zhou, T. Emura, K. Hidaka, B. Tuesuwan, H. Sugiyama,
    ACS Nano, 9, 9922-9929 (2015).
  • Direct visualization of walking motions of a photo-controlled DNA nanomachine on the DNA nanostructure.
    Y. Yang, M. Goetzfried, K. Hidaka, M. You, W. Tan, H. Sugiyama, M. Endo,
    Nano Lett. 15, 6672-6676 (2015).
  • Lipid bilayer-supported two-dimensional self-assembly of DNA origami nanostructures.
    Y. Suzuki, M. Endo, H. Sugiyama,
    Nature Communications, 6, 8052 (2015).
  • Single-Molecule Visualization of the Activity of Zn2+-Dependent DNAzyme.
    M. Endo, Y. Takeuchi, Y. Suzuki, T. Emura K. Hidaka, F. Wang, I. Willner, H. Sugiyama,
    Angew. Chem. Int. Ed. 54, 10550-10554 (2015).
  • Efficient amplification of self-gelling polypod-like structured DNA by rolling circle amplification and enzymatic digestion.
    T. Yata, Y. Takahashi, K. Hidaka, H. Sugiyama, M. Endo, Y. Takakura, M. Nishikawa,
    Sci. Rep. 5, 14979 (2015).
  • Linking Two DNA Duplexes with a Rigid Linker for DNA Nanotechnology.
    R. Tashiro, M. Iwamoto, H. Morinaga, T. Emura, K. Hidaka, M. Endo, H. Sugiyama,
    Nucleic Acids Res. 43, 6692-6700 (2015).
  • Mimicking membrane-related biological events by DNA origami nanotechnology.
    Y. Suzuki, M. Endo, H. Sugiyama,
    ACS Nano, 9, 3418-3420 (2015).
  • DNA nanotechnology: Measuring chloride in live cells.
    M. Endo, H. Sugiyama
    Nature Nanotechnology, 10, 569-570 (2015).
  • Small molecule binding to G-hairpin and G-triplex: A new insight in anticancer drug design targeting G-rich regions.
    A. Rajendran, M. Endo, K. Hidaka, M.-P. Teulade-Fichou, J.-L. Mergny, H. Sugiyama,
    Chem. Commun. 51, 9181-9184 (2015).
  • Studying RNAP–promoter interactions using atomic force microscopy.
    Y. Suzuki, M. Endo, H. Sugiyama,
    Methods, 86, 4-9 (2015).
  • Atomic Force Microscopy Analysis of Orientation and Bending of Oligodeoxynucleotides in Polypod-like Structured DNA.
    T. Shiomi, M. Tan, N. Takahashi, M. Endo, T. Emura, K. Hidaka, H. Sugiyama, Y. Takahashi, Y. Takakura, M. Nishikawa,
    Nano Res. 8, 3764-3771 (2015).
  • Self-assembling DNA dendrimer for effective delivery of immunostimulatory CpG DNA to immune cells.
    K. Mohri, E. Kusuki, S. Ohtsuki, N. Takahashi, M. Endo, K. Hidaka, H. Sugiyama,Y. Takahashi, Y. Takakura, M. Nishikawa,
    Biomacromolecules,16, 1095-1101 (2015).
  • Optimal Arrangement of Four Short DNA Strands for Delivery of Nucleic Acid Drugs to Immune Cells.
    S. Ohtsuki, N. Matsuzaki, K. Mohri, M. Endo, T. Emura, K. Hidaka, H. Sugiyama, Y. Takahashi, Y. Takakura, M. Nishikawa,
    Nucleic Acid Theraputics, 25, 245−253 (2015).
  • Folding RNA-protein complex into designed nanostructures.
    T. Shibata, Y. Suzuki, H. Sugiyama, M. Endo, H. Saito,
    RNA Scaffolds: Methods and Protocols, Luc Ponchon (ed.),
    Methods in Molecular Biology, vol. 1316, 169-179 (2015).
  • Direct Observation of G-Quadruplexes and their Folding Intermediates.
    A. Rajendran, Y. Li, M. Endo, H. Sugiyama,
    Biological relevance and therapeutic applications of DNA- and RNA-quadruplexes: double helix versus quadruple helix, David Monchaud Ed., Future Science, pp 38-54 (2015).

2014   

  • Single-Molecule Imaging of Dynamic Motions of Biomolecules in DNA Origami Nanostructures Using High-Speed Atomic Force Microscopy.
    M. Endo, H. Sugiyama,
    Acc. Chem. Res. 47, 1645-1653 (2014).
  • State-of-the-Art High-Speed Atomic Force Microscopy for the Investigation of Single-Molecular Dynamics of Proteins.
    A. Rajendran, M. Endo, H. Sugiyama,
    Chem. Rev. 114, 1493-1520 (2014).
  • Dynamic Assembly/Disassembly Processes of Photoresponsive DNA Origami Nanostructures Directly Visualized on a Lipid Membrane Surface.
    Y. Suzuki, M. Endo, Y. Yang, H. Sugiyama,
    J. Am. Chem. Soc. 136, 1714-1717 (2014).
  • DNA origami based visualization system for studying site-specific recombination events.
    Y. Suzuki, M. Endo, Y. Katsuda, K. Ou, K. Hidaka, H. Sugiyama,
    J. Am. Chem. Soc. 136, 211-218 (2014).
  • Single-Molecule Mechanochemical Sensing Using DNA Origami Nanostructures.
    D. Koirala, P. Shrestha, T. Emura, K. Hidaka, S. Mandal, M. Endo, H. Sugiyama, H. Mao,
    Angew. Chem. Int. Ed. 53, 8137-8141 (2014).
  • Helical DNA Origami Tubular Structures with Various Sizes and Arrangements.
    M. Endo, S. Yamamoto, T. Emura, K. Hidaka, N. Morone, J. E. Heuser, H. Sugiyama,
    Angew. Chem. Int. Ed. 53, 7484-7490 (2014).
  • Direct and single-molecule visualization of the solution-state structure of G-hairpin and G-triplex intermediates.
    A. Rajendran, M. Endo, K. Hidaka, H. Sugiyama,
    Angew. Chem. Int. Ed. 53, 4107–4112 (2014).
  • Preparation of Chemically Modified RNA Origami Nanostructures.
    M. Endo, Y. Takeuchi, T. Emura, K. Hidaka, H. Sugiyama,
    Chem. Eur. J. 20, 15330-15333 (2014).
  • Photoresponsive DNA Nanocapsule Having an Open/Close System for Capture and Release of Nanomaterials.
    T. Takenaka, M. Endo, Y. Suzuki, Y. Yang, T. Emura, K. Hidaka, T. Kato, T. Miyata, K. Namba, H. Sugiyama,
    Chem. Eur. J. 20, 14951-14954 (2014).
  • Single molecule visualization and characterization of Sox2-Pax6 complex formation on a regulatory DNA element using a DNA origami frame.
    S. Yamamoto, D. De, K. Hidaka, K. Kim, M. Endo, H. Sugiyama,
    Nano Lett. 14, 2286−2292 (2014).
  • Engineering RNA-Protein Complexes with Different Shapes for Imaging and Therapeutic Applications.
    E. Osada, Y. Suzuki, K. Hidaka, H. Ohno, H. Sugiyama, M. Endo, H. Saito,
    ACS Nano, 8, 8130-8140 (2014).
  • Dynamic analysis of Holiday Junction resolving enzyme in a DNA origami nanostructure.
    Y. Suzuki, M. Endo, C. Cañas, S. Ayora, J. C. Alonso, H. Sugiyama, K. Takeyasu,
    Nucleic Acids Res. 42, 7421-7428 (2014).
  • Lock-and-key mechanism for the controllable fabrication of DNA origami structures.
    A. Rajendran, M. Endo, K. Hidaka, N. Shimada, A. Maruyama, H. Sugiyama,
    Chem. Commun. 50, 8743-8746 (2014).
  • Direct observation of the dual-switching behaviors corresponding to the state transition in a DNA nanoframe.
    Y. Yang, M. Endo, Y. Suzuki, K. Hidaka, H. Sugiyama,
    Chem. Commun. 50, 4211-4213 (2014).
  • AFM analysis of changes in nucleosome wrapping induced by DNA epigenetic modification.
    S. Kizaki, Y. Suzuki, T. Takenaka, M. Endo, H. Sugiyama,
    Biomater. Sci. 2, 1399-1403 (2014).
  • G-Quadruplex Binding Ligand-Induced DNA Synapsis Inside a DNA Origami Frame.
    A. Rajendran, M. Endo, K. Hidaka, P. L. T. Tran, J.-L. Mergny, H. Sugiyama,
    RSC Advances, 4, 6346-6355 (2014).

2013

  • HIV-1 Nucleocapsid Proteins as Molecular Chaperones for Tetramolecular Antiparallel G-Quadruplex Formation.
    A. Rajendran, M. Endo, K. Hidaka, P. L. T. Tran, J.-L. Mergny, R. J. Gorelick, H. Sugiyama,
    J. Am. Chem. Soc. 135, 18575-18585 (2013).
  • Direct and real-time observation of rotary movement of a DNA nanomechanical device.
    A. Rajendran, M. Endo, K. Hidaka, H. Sugiyama,
    J. Am. Chem. Soc. 135, 1117-1123 (2013).
  • Regulation of B–Z Conformational Transition and Complex Formation with a Z-Form Binding Protein by Introduction of Constraint to Double-Stranded DNA by using a DNA Nanoscaffold.
    M. Endo, M. Inoue, Y. Suzuki, C. Masui, H. Morinaga, K. Hidaka, H. Sugiyama,
    Chem. Eur. J. 19, 16887-16890 (2013).
  • Controlling the stoichiometry and strand polarity of a tetramolecular G-quadruplex structure by using a DNA origami frame.
    A. Rajendran, M. Endo, K. Hidaka, P. L. T. Tran, J.-L. Mergny, H. Sugiyama,
    Nucleic Acids Res. 41, 8738-8747 (2013).
  • RNA-templated DNA origami structures.
    M. Endo, S. Yamamoto, K. Tatsumi, T. Emura, K. Hidaka, H. Sugiyama,
    Chem. Commun. 49, 2879-2881 (2013).
  • Control of the two-dimensional crystallization of DNA origami with various loop arrangements.
    A. Rajendran, M. Endo, K. Hidaka, H. Sugiyama,
    Chem. Commun. 49, 686-688 (2013).
  • DNA origami technology for biomaterials applications.
    M. Endo, Y. Yang, H. Sugiyama,
    Biomater. Sci., 1, 347-360 (2013).
  • G-quadruplex nanostructures probed at the single molecular level by force-based methods.
    S. Dhakal, H. Mao, A. Rajendran, M. Endo, H. Sugiyama,
    Guanine quartets: Structure and application, Royal Society of Chemistry, 73-85 (2013).

2012

  • Photo-Controllable DNA Origami Nanostructures Assembling into Predesigned Multiorientational Patterns.
    Y. Yang, M. Endo, K. Hidaka, H. Sugiyama,
    J. Am. Chem. Soc. 134, 20645-20653 (2012).
  • Sequence-Selective Single-Molecule Alkylation with a Pyrrole-Imidazole Polyamide Visualized in a DNA Nanoscaffold.
    T. Yoshidome, M. Endo, G. Kashiwazaki, K. Hidaka, T. Bando, H. Sugiyama,
    J. Am. Chem. Soc. 134, 4654-4660 (2012).     
  • Transcription Regulation System Mediated by Mechanical Operation of DNA Nanostructure.
    M. Endo, R. Miyazaki, T. Emura, K. Hidaka, H. Sugiyama,
    J. Am. Chem. Soc. 134, 2852-2855 (2012).
  • A DNA-based molecular motor that can navigate a network of tracks.
    S. F. J. Wickham, J. Bath, Y. Katsuda, M. Endo, K. Hidaka, H. Sugiyama, A. J. Turberfield,
    Nature Nanotechnology, 7, 169-173 (2012).
  • Single-Molecule Visualization of the Hybridization and Dissociation of Photoresponsive Oligonucleotides and Their Reversible Switching Behavior in a DNA Nanostructure.
    M. Endo, Y. Yang, Y. Suzuki, K. Hidaka, H. Sugiyama,
    Angew. Chem. Int. Ed. 51, 10518-10522 (2012).
  • Direct Visualization of the Movement of a Single T7 RNA Polymerase and Transcription on a DNA Nanostructure.
    M. Endo, K. Tatsumi, K. Terushima, Y. Katsuda, K. Hidaka, Y. Harada, H. Sugiyama,
    Angew. Chem. Int. Ed. 51, 8778-8782 (2012).
  • Single-Molecule Analysis Using DNA Origami.
    A. Rajendran, M. Endo, H. Sugiyama,
    Angew. Chem. Int. Ed. 51, 874-890 (2012).
  • Zinc-Finger Proteins for Site-Specific Protein Positioning on DNA-Origami Structures.
    E. Nakata, L. Fong, C. Uwatoko, S. Kiyonaka, Y. Mori, Y. Katsuda, M. Endo, H. Sugiyama, T. Morii,
    Angew. Chem. Int. Ed. 51, 2421-2424 (2012).
  • Design and Development of Nanosized DNA Assemblies in Polypod-like Structures as Efficient Vehicles for Immunostimulatory CpG Motifs to Immune Cells.
    K. Mohri, M. Nishikawa, N. Takahashi, N. Matsuoka, M. Endo, K. Hidaka, H. Sugiyama, Y. Takahashi, Y. Takakura,
    ACS Nano, 6, 5931-5940 (2012).
  • Structure and Functional Analysis of Proteins by High-Speed Atomic Force Microscopy.
    A. Rajendran, M. Endo, H. Sugiyama,
    Adv. Protein Chem. Struct. Biol. 87, 5-55 (2012).
  • DNA Origami: Synthesis and Self-Assembly.
    A. Rajendran, M. Endo, H. Sugiyama,
    Current Protocols in Nucleic Acids Chem. 48, 12.9.1-12.9.18 (2012).

2011

  • Direct observation of stepwise movement of a synthetic molecular transporter.
    S. F. J. Wickham, M. Endo, Y. Katsuda, K. Hidaka, J. Bath, H. Sugiyama, A. J. Turberfield,
    Nature Nanotechnology, 6, 166-169 (2011).
  • Photo-Cross-Linking-Assisted Thermal Stability of DNA Origami Structures and Its Application for Higher-Temperature Self-Assembly.
    A. Rajendran, M. Endo, K. Hidaka, H. Sugiyama,
    J. Am. Chem. Soc. 133, 14488-14491 (2011).
  • Programmed Two-Dimensional Self-Assembly of Multiple DNA Origami Jigsaw Pieces.
    A. Rajendran, M. Endo, Y. Katsuda, K. Hidaka, H. Sugiyama,
    ACS Nano, 5, 665-671 (2011).
  • Programmed placement of gold nanoparticles onto a slit-type DNA origami scaffold.
    M. Endo, Y. Yang, T. Emura, K. Hidaka, H. Sugiyama,
    Chem. Commun. 47, 10743–10745 (2011).
  • Two-dimensional DNA origami assemblies using a four-way connector.
    M. Endo, T. Sugita, A. Rajendran, Y. Katsuda, T. Emura, K. Hidaka, H. Sugiyama,
    Chem. Commun. 47, 3213-3215 (2011).
  • Direct AFM Observation of an Opening Event of a DNA Cuboid Constructed via a Prism Structure.
    M. Endo, K. Hidaka, H. Sugiyama,
    Org. Biomol. Chem. 9, 2075-2077 (2011).
  • Recent Progress of DNA origami technology.
    M. Endo, H. Sugiyama,
    Current Protocols in Nucleic Acids Chem. 45, 12.8.1-12.8.19 (2011).

2010

  • Visualization of Dynamic Conformational Switching of the G-Quadruplex in a DNA Nanostructure.
    Y. Sannohe, M. Endo, Y. Katsuda, K. Hidaka, H. Sugiyama
    J. Am. Chem. Soc. 132, 16311–16313 (2010).
  • Regulation of DNA Methylation Using Different Tensions of Double Strands Constructed in a Defined DNA Nanostructure.
    M. Endo, Y. Katsuda, K. Hidaka, H. Sugiyama,
    J. Am. Chem. Soc. 132, 1592–1597 (2010).
  • A versatile DNA nanochip for direct analysis of DNA base-excision repair.
    M. Endo, Y. Katsuda, K. Hidaka, H. Sugiyama,
    Angew. Chem. Int. Ed. 49, 9412–9416 (2010).
  • Programmed-Assembly System Using DNA Jigsaw Pieces.
    M. Endo, T. Sugita, Y. Katsuda, K. Hidaka, H. Sugiyama,
    Chem. Eur. J. 16, 5362–5368 (2010).

2009

  • DNA Prism Structures Constructed by Folding of Multiple Rectangular Arms.
    M. Endo, K. Hidaka, T. Kato, K. Namba, H. Sugiyama,
    J. Am. Chem. Soc. 131, 15570–15571 (2009).
  • Chemical Approaches to DNA Nanotechnology.
    M. Endo, H. Sugiyama,
    ChemBioChem,10, 2420-2443 (2009).

著書・総説・解説

  • DNAナノテクノロジーと1分子科学 ~1分子で捉えるユニークな生体分子反応~
    遠藤 政幸
    日本化学会編『CSJカレントレビュー 核酸化学のニュートレンド』化学同人、in press (2021).
  • DNAオリガミを利用した1分子可視化と計測
    遠藤 政幸
    講談社サイエンティフィック『核酸科学ハンドブック』杉本直己(編) 講談社、193-200 (2021).
  • DNAオリガミを使った分子ナノナノマシン
    遠藤 政幸
    電気学会誌、Vol. 140, No. 9, 579-581 (2020).
  • DNAオリガミによるプラズモニック構造体の構築
    遠藤 政幸
    光学、Vol. 49, No. 4, 152-158 (2020).
  • 脂質膜表面におけるDNAオリガミの二次元自己集合化
    鈴木 勇揮、遠藤 政幸、杉山 弘
    生物物理、Vol. 59, No. 2, 103-105 (2019).
  • DNAから作るナノスケールの構造体―そのデザインと作成―
    遠藤 政幸
    化学と教育、Vol. 66, No. 2, 88-91 (2018).
  • DNA分子マシン
    遠藤 政幸、杉山 弘
    日本化学会編『CSJカレントレビュー 分子マシンの展開』 化学同人 pp140-148 (2017).
  • DNAオリガミの応用 構造から機能へ
    遠藤 政幸
    現代化学、No. 544, 40-45 (2016).
  • DNA ナノ構造体を利用したDNA 構造変化の1分子イメージング
    遠藤 政幸、杉山 弘
    DOJIN BIOSCIENCE SERIES『1分子生物学』、化学同人 pp274-276 (2014).
  • DNA オリガミ構造体を利用した1分子イメージングシステムの開発
    遠藤 政幸、杉山 弘
    新材料・新素材シリーズ『超分子材料の設計と応用展開』、シーエムシー出版、pp101-113 (2014).
  • DNA オリガミ法を用いた次世代ナノシステム
    遠藤 政幸、杉山 弘
    化学工業、Vol. 65, No. 1, 42-48 (2014).
  • DNAオリガミによる生体分子の動的な観察システム
    遠藤 政幸、杉山 弘
    現代化学、No. 508, 26-31 (2013).
  • DNAナノ構造上を動くDNA分子マシーン
    遠藤 政幸、杉山 弘
    高分子, Vol. 62, No.3, 129-131 (2013).
  • DNAオリガミを使った1分子解析
    遠藤 政幸、杉山 弘
    生物物理, Vol. 53,No. 3,153-157 (2013).
  • DDS 研究のための最新機器 (12) 高速原子間力顕微鏡
    遠藤 政幸、西川 元也
    Drug delivery system, 日本DDS学会, Vol.28, No. 2, 150-152 (2013).
  • ナノ空間でDNA 1 分子の動作を捉える―極小の分子システムで操るナノマシン
    遠藤 政幸、杉山 弘
    化学, Vol. 37, No. 5, 32-37 (2012).
  • DNAオリガミによる1分子観察系の構築
    遠藤 政幸、杉山 弘
    『疾患克服を目指したケミカルバイオロジー』実験医学2012年増刊号, Vol. 30, No. 7, 180-186 (2012).
  • DNAオリガミ構造体と1分子観察への応用
    遠藤 政幸、杉山 弘
    化学工業, Vol. 63, No. 2, 36-41 (2012).
  • DNAオリガミによるメゾスケール多次元構造の構築とナノ空間での機能発現
    遠藤 政幸、 杉山 弘
    有機合成化学協会誌, Vol. 69, No. 12, 1352-1362 (2011).
  • DNAオリガミ法による多次元構造体の構築と高次機能化
    遠藤 政幸、 杉山 弘
    未来材料, Vol. 11, No. 5, 2-10 (2011).
  • DNAナノ空間での生体分子のコントロールと直接的な観察
    遠藤 政幸、 杉山 弘
    パリティ、Vol. 26、No. 1, 72-74 (2011).
  • DNAナノ構造の設計・構築とその応用
    遠藤 政幸、杉山 弘
    BIO INDUSTRY, Vol. 27, No. 10, 48-54 (2010).
  • DNAとジグソーパズル
    遠藤 政幸、杉山 弘
    化学、Vol 65, No. 6, 49-52 (2010).

 




バナースペース

DNAナノテクノロジーグループ
京都大学大学院理学研究科
京都大学高等研究院

〒606-8501
京都市左京区吉田牛ノ宮町